Evidence map›Paper›PMID 36381588›Full record

ArticleCurrent opinion in physiology2019

Somatosensation a la mode: plasticity and polymodality in sensory neurons.

Edward C Emery, John N Wood

Abstract read
In one paragraph

Article in Current opinion in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Sensory integration of food and population density during the diapause exit decision involves insulin-like signaling inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Properties and Differential Expression of HFrontiers in physiology · 2021
    Review
  10. Review
  11. Sodium channels NaNeurobiology of pain (Cambridge, Mass.)
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Edward C EmeryMolecular Nociception Group, Wolfson Institute for Biomedical Research, The Cruciform Building, University College London, Gower Street, WC1E 6BT, United Kingdom.
John N WoodMolecular Nociception Group, Wolfson Institute for Biomedical Research, The Cruciform Building, University College London, Gower Street, WC1E 6BT, United Kingdom.

Funding

Versus Arthritis 21950Wellcome Trust 200183
6 · The paper itself

Abstract

Our understanding of how peripheral damage-sensing neurons (nociceptors) respond to noxious stimuli is fundamental to the development of effective analgesics. To date, numerous studies have presented diverging hypotheses on how nociceptors encode modality-specific stimuli, including labelled-line, intensity dependence or pattern theory. In this short review, we appraise data from electrophysiological, behavioural, imaging and molecular expression studies from the last 60 years, in order to obtain a coherent view of modality-specific sensing in peripheral sensory neurons. We propose a mechanistic explanation for the broad range of values obtained for the incidence of polymodal nociceptors that reconciles apparently contradictory data.

Identifiers

PMID36381588
PMCPMC7613802

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.