Evidence map›Paper›PMID 36381497›Full record

ArticleGeriatric orthopaedic surgery & rehabilitation2022

Risk of Mortality for Proximal Femoral Fracture in Patients With and Without COVID-19. A Retrospective Cohort Study.

Ashley Holub, Montsant Jornet-Gibert, Jill Ruppenkamp, Chantal E Holy, Juan Daccach, Pere Torner, Pedro Caba-Doussoux, Josep Maria Muñoz Vives

Abstract read
In one paragraph

Article in Geriatric orthopaedic surgery & rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashley HolubEpidemiology & Real-World Data Sciences, Johnson & Johnson MedTech, New Brunswick, NJ, USA.ORCID https://orcid.org/0000-0003-0894-9184
Montsant Jornet-GibertDepartment of Orthopaedic Surgery and Traumatology, Hospital Clinic de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0001-8915-2104
Jill RuppenkampEpidemiology & Real-World Data Sciences, Johnson & Johnson MedTech, New Brunswick, NJ, USA.
Chantal E HolyEpidemiology & Real-World Data Sciences, Johnson & Johnson MedTech, New Brunswick, NJ, USA.ORCID https://orcid.org/0000-0002-5901-1156
Juan DaccachMedical Safety, Office of the Chief Medical Officer, Johnson & Johnson, New Brunswick, NJ, USA.
Pere TornerDepartment of Orthopaedic Surgery and Traumatology, Hospital Clinic de Barcelona, Barcelona, Spain.
Pedro Caba-DoussouxDepartment of Orthopaedic Surgery and Traumatology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Josep Maria Muñoz VivesDepartment of Orthopaedic Surgery and Traumatology, Althaia, Xarxa Assistencial Universitària de Manresa, Manresa, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: SARS-CoV-2 (COVID-19) has resulted in a widespread loss of lives, morbidity, and major disruptions to the healthcare system. Hip fractures are an emergent condition which require early intervention to reduce increased risk of mortality and morbidity. Infection of SARS-CoV-2 may contribute to increased mortality due to the role of infection and immune response. This study investigated the impact of COVID-19 infection (defined by clinical symptoms) on mortality following proximal femoral fracture (PFF) repair procedures. Methods: This study was a retrospective cohort study. Data from the Premier Healthcare Database Results: A total of N = 73 953 subjects were enrolled for the 2019 period, and a total of N = 34 842 subjects were enrolled for the COVID period. For the 2019 period, subjects who had a PFF procedure and who had flu/COVID-like illness had 2.47 (CI:2.11, 2.88) times the odds of mortality compared to those who did not have flu/COVID-like illness. Subjects who had a PFF procedure and who had flu/COVID-like illness during the COVID period had 2.85 times (CI:2.36, 3.42) the odds of mortality compared to those who did not have flu/COVID-like illness. For the COVID period, within subjects who did not have a PFF procedure, those with flu/COVID-like illness had increased odds of mortality compared to those who did not have flu/COVID-like illness (OR:2.26, CI:1.57, 3.21). Conclusions: Hip fractures present high risk for mortality and morbidity, where timely intervention is critical to improved outcomes. Presence of infection such as flu/COVID-like illness may influence mortality in patients undergoing hip fracture repair procedures. Consideration of infection status as a comorbidity is important to proper management and achieving optimal outcomes.

Indexed as

COVID-19hip fracturemortalityproximal femoral fracturereal world dataSARS-cov-2

Identifiers

PMID36381497
PMCPMC9659485

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.