Clinicopathologic characteristics of low-grade thyroid-like nasopharyngeal papillary adenocarcinoma: a case report.

Haoyue Hu, Lang Long, Xue Fan, Jun He

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Article in International journal of clinical and experimental pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

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1 citing paper in PubMed.

A case report of thyroid-like low-grade nasopharyngeal papillary adenocarcinoma with literature review.Frontiers in oncology · 2026
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4 authors.

Haoyue HuDepartment of Medical Oncology, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, Medicine School of University of Electronic Science and Technology Chengdu 610041, China.

Lang LongDepartment of Pediatric Respiratory and Neurology, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture Enshi, China.

Xue FanDepartment of Medical Oncology, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, Medicine School of University of Electronic Science and Technology Chengdu 610041, China.

Jun HeDepartment of Oncology, The Third Hospital of Mianyang (Sichuan Mental Health Center) Mianyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low-grade thyroid-like nasopharyngeal papillary adenocarcinoma is a rare malignant tumor characterized by morphologic analogy to papillary thyroid carcinoma and aberrant thyroid transcription factor-1 (TTF-1) expression. To date, a limited number of cases have been reported in the literature. We report a case of a 20-year-old Chinese male patient with complaints of headaches and nosebleeds for 5 months. The histopathologic examination showed thyroid-like low-grade nasopharyngeal papillary adenocarcinoma that was confirmed by immunohistochemical staining. The patient was treated with macroscopic complete resection without adjuvant therapy. The epidemiologic characteristics and clinical and pathologic features of the disease are summarized. In addition, we summarize the treatments used previously. In general, TL-LGNPPA is a very rare low-grade adenocarcinoma with aberrant expression of TTF-1, and its diagnosis depends on morphology and immunophenotype. The prognosis is good.

Indexed as

clinicopathologic characteristicsLow-grade thyroid-like nasopharyngeal papillary adenocarcinomasurgerytherapy

Identifiers

PMID36381418

PMCPMC9638840

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