Evidence map›Paper›PMID 36381377›Full record

ArticleClinical kidney journal2022

Standardization of serum creatinine is essential for accurate use of unbiased estimated GFR equations: evidence from three cohorts matched on renal function.

Hans Pottel, Etienne Cavalier, Jonas Björk, Ulf Nyman, Anders Grubb, Natalie Ebert, Elke Schaeffner, Björn O Eriksen, Toralf Melsom, Edmund J Lamb and 9 more

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Combined Creatinine and Cystatin C Equations Improve Estimation of Glomerular Filtration Rate in Kidney Transplant Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 7 countries.

Hans PottelDepartment of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.ORCID https://orcid.org/0000-0003-0074-8919
Etienne CavalierDepartment of Clinical Chemistry, University of Liège, CHU Sart Tilman, Liège, Belgium.
Jonas BjörkDivision of Occupational and Environmental Medicine, Lund University, Lund, Sweden.ORCID https://orcid.org/0000-0003-1883-2000
Ulf NymanDepartment of Translational Medicine, Division of Medical Radiology, Lund University, Malmö, Sweden.
Anders GrubbDepartment of Clinical Chemistry, Skåne University Hospital, Lund, Lund University, Sweden.
Natalie EbertCharité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany.ORCID https://orcid.org/0000-0002-4463-3315
Elke SchaeffnerCharité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany.
Björn O EriksenSection of Nephrology, University Hospital of North Norway and Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsö, Norway.
Toralf MelsomSection of Nephrology, University Hospital of North Norway and Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsö, Norway.
Edmund J LambClinical Biochemistry, East Kent Hospitals University NHS Foundation Trust, Canterbury, UK.
Christophe MariatService de Néphrologie, Dialyse et Transplantation Rénale, Hôpital Nord, CHU de Saint-Etienne, France.
Laurence DubourgNéphrologie, Dialyse, Hypertension et Exploration Fonctionnelle Rénale, Hôpital Edouard Herriot, Hospices Civils de Lyon, France.
Magnus HanssonFunction area Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital Huddinge and Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.
Karin LittmannDivision of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institute, Huddinge, Sweden.
Per-Ola SundinDepartment of Geriatrics, School of Medical Sciences, Örebro University, Örebro, Sweden.ORCID https://orcid.org/0000-0001-8128-732X
Anna ÅkessonDivision of Occupational and Environmental Medicine, Lund University, Lund, Sweden.
Anders LarssonDepartment of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden.
Andrew RuleDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Pierre DelanayeNephrology-Dialysis-Transplantation, University of Liège, CHU Sart Tilman, Liège, Belgium.ORCID https://orcid.org/0000-0002-1480-5761
Lund University · SEBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEUniversity Hospital of North Norway · NOUniversity of Liège · BEEast Kent Hospitals University NHS Foundation Trust · GBHôpital Nord · FRHospices Civils de Lyon · FRKarolinska Institutet · SEKarolinska University Hospital · SEKU Leuven · BEMayo Clinic · USÖrebro University · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Differences in the performance of estimated glomerular filtration rate (eGFR) equations have been attributed to the mathematical form of the equations and to differences between patient demographics and measurement methods. We evaluated differences in serum creatinine (SCr) and eGFR in cohorts matched for age, sex, body mass index (BMI) and measured GFR (mGFR). Methods: White North Americans from Minnesota ( Results: For 305 matched individuals, mean SCr (mg/dL) was not different between the Minnesota and EKFC cohorts (females 0.83 ± 0.20 versus 0.86 ± 0.23, males 1.06 ± 0.23 versus 1.12 ± 0.37; Conclusion: Significant differences in SCr concentrations between the Minnesota and EKFC cohorts versus CRIC were observed in subjects with the same level of mGFR and equal demographic characteristics and can be explained by the difference in SCr calibration.

Indexed as

serum creatininestandardizationunbiased GFR estimation

Identifiers

PMID36381377
PMCPMC9664577
OpenAlexW4289637598

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.