Evidence map›Paper›PMID 36381226›Full record

ArticleCell reports. Physical science2022

Advances, obstacles, and opportunities for machine learning in proteomics.

Heather Desaire, Eden P Go, David Hua

Abstract read
In one paragraph

Article in Cell reports. Physical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Heather DesaireDepartment of Chemistry, University of Kansas, Lawrence, KS 66045, USA.
Eden P GoDepartment of Chemistry, University of Kansas, Lawrence, KS 66045, USA.
David HuaDepartment of Chemistry, University of Kansas, Lawrence, KS 66045, USA.

Funding

Mass Spectrometry Measurements for Complex PTMsR35GM130354 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI DESAIRE, HEATHER R · 2019 to 2023
$1.9M
A Study of Race Differences in Alzheimer's Disease BiomarkersRF1AG072760 · NIA · UNIVERSITY OF KANSAS LAWRENCE · PI DESAIRE, HEATHER R · 2021 to 2021
$1.1M
NIA NIH HHS RF1 AG072760NIGMS NIH HHS R35 GM130354
6 · The paper itself

Abstract

The fields of proteomics and machine learning are both large disciplines, each producing well over 5,000 publications per year. However, studies combining both fields are still relatively rare, with only about 2% of recent proteomics papers including machine learning. This review, which focuses on the intersection of the fields, is intended to inspire proteomics researchers to develop skills and knowledge in the application of machine learning. A brief tutorial introduction to machine learning is provided, and research advances that rely on both fields, particularly as they relate to proteomics tools development and biomarker discovery, are highlighted. Key knowledge gaps and opportunities for scientific advancement are also enumerated.

Identifiers

PMID36381226
PMCPMC9648337

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.