Evidence map›Paper›PMID 36380958›Full record

ArticleRSC advances2022

Transformation of theranostic alginate-based microbubbles from raspberry-like to core-shell-like microbubbles and

Meng-Yi Bai, Tsai-Hsuan Chen, Yu-Chi Wang, Yu-Ju Lai

Abstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meng-Yi BaiGraduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology No. 43, Keelung Rd, Sec. 4, Da'an Dist. Taipei City 10607 Taiwan mybai@mail.ntust.edu.tw.ORCID https://orcid.org/0000-0002-6329-5454
Tsai-Hsuan ChenGraduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology No. 43, Keelung Rd, Sec. 4, Da'an Dist. Taipei City 10607 Taiwan mybai@mail.ntust.edu.tw.
Yu-Chi WangDepartment of Obstetric and Gynecology, Tri-Service General Hospital, National Defense Medical Centre Taiwan.
Yu-Ju LaiDepartment of Obstetric and Gynecology, Tri-Service General Hospital, National Defense Medical Centre Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study alginate-based microbubbles with a raspberry-like or core-shell-like morphology and with an average particle size of 553.6 ± 69.6 μm were synthesized; this was done through a novel procedure of transforming the structure with a 40 kHz ultrasonication which also stimulated the release of the components inside. Through the use of the electrospray technique in conjunction with agitation processes, components such as shikonin (SHK) and indocyanine green (ICG) were simultaneously encapsulated in alginate microbubbles to produce SHK-ICG alginate microbubbles; these microbubbles had half-maximal inhibitory concentrations of approximately 2.08 and 4.43 μM toward CP70 and SKOV3 ovarian cancer-cell lines, respectively, in an

Identifiers

PMID36380958
PMCPMC9641574

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.