Evidence map›Paper›PMID 36380939›Full record

ArticleRSC advances2022

Simple fluorescence chemosensor for the detection of calcium ions in water samples and its application in bio-imaging of cancer cells.

Maral Salek-Maghsoodi, Zahra Golsanamlu, Sanam Sadeghi-Mohammadi, Masoud Gazizadeh, Jafar Soleymani, Reza Safaralizadeh

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maral Salek-MaghsoodiPharmaceutical Analysis Research Center, Tabriz University of Medical Sciences Tabriz Iran jsoleymanii@gmail.com soleymanij@tbzmed.ac.ir +98 41 3337 5365.
Zahra GolsanamluPharmaceutical Analysis Research Center, Tabriz University of Medical Sciences Tabriz Iran jsoleymanii@gmail.com soleymanij@tbzmed.ac.ir +98 41 3337 5365.
Sanam Sadeghi-MohammadiTuberculosis and Lung Diseases Research Center, Tabriz University of Medical Sciences Tabriz Iran.
Masoud GazizadehLiver and Gastrointestinal Research Center, Tabriz University of Medical Sciences Tabriz Iran.
Jafar SoleymaniPharmaceutical Analysis Research Center, Tabriz University of Medical Sciences Tabriz Iran jsoleymanii@gmail.com soleymanij@tbzmed.ac.ir +98 41 3337 5365.ORCID https://orcid.org/0000-0002-8316-5104
Reza SafaralizadehDepartment of Biology, Faculty of Natural Sciences, Tabriz University Tabriz Iran.
Tabriz University of Medical Sciences · IRUniversity of Tabriz · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article describes the design, synthesis and characterization of a sensor suitable for practical measurement of ionized calcium in water samples and cancer cells. Calcium is an important ion in living organs and works as a messenger in several cellular functions. A lack of Ca ions interrupts the immune system and can lead to several diseases. A novel magnetic-polydopamine nanoparticle (PDNP)/rhodamine B (RhB)/folic acid (FA) nanoparticle was developed for the determination of calcium ions in MCF 7 cell lysates and water samples. Furthermore, the produced nanoparticle was employed for bioimaging of folate receptor (FR)-overexpressed cancer cells. This nanoprobe displayed a bright photoluminescence emission at 576 nm under an excitation wavelength of 420 nm. In the presence of calcium ions, the fluorescence emission of the MNPs-PDNPs/RhB/FA probe was proportionally decreased from 20 ng mL

Identifiers

PMID36380939
PMCPMC9631868
OpenAlexW4309243681

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.