Evidence map›Paper›PMID 36380895›Full record

ArticleNeurology. Clinical practice2022

A Review of Practices Around Determination of Death by Neurologic Criteria by an Organ Procurement Organization in the WAMI Region.

Abhijit Vijay Lele, Sarah Wahlster, Ian Bost, Dominic Adorno, Candy Wells, Kevin O'Connor, David Greer, Michael J Souter

Abstract read
In one paragraph

Article in Neurology. Clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abhijit Vijay LeleDepartment of Anesthesiology and Pain Medicine (AVL, MJS), Harborview Medical Center, University of Washington; Neurocritical Service (AVL, SW, MJS), Harborview Medical Center, University of Washington; Department of Neurological Surgery (AVL, MJS), Harborview Medical Center, University of Washington; Department of Neurology (SW), Harborview Medical Center, University of Washington, Seattle; LifeCenter Northwest (IB, DA, CW, KOC), Bellevue, WA; and Department of Neurology (DG), Boston University School of Medicine and Boston Medical Center, MA.
Sarah WahlsterDepartment of Anesthesiology and Pain Medicine (AVL, MJS), Harborview Medical Center, University of Washington; Neurocritical Service (AVL, SW, MJS), Harborview Medical Center, University of Washington; Department of Neurological Surgery (AVL, MJS), Harborview Medical Center, University of Washington; Department of Neurology (SW), Harborview Medical Center, University of Washington, Seattle; LifeCenter Northwest (IB, DA, CW, KOC), Bellevue, WA; and Department of Neurology (DG), Boston University School of Medicine and Boston Medical Center, MA.
Ian BostDepartment of Anesthesiology and Pain Medicine (AVL, MJS), Harborview Medical Center, University of Washington; Neurocritical Service (AVL, SW, MJS), Harborview Medical Center, University of Washington; Department of Neurological Surgery (AVL, MJS), Harborview Medical Center, University of Washington; Department of Neurology (SW), Harborview Medical Center, University of Washington, Seattle; LifeCenter Northwest (IB, DA, CW, KOC), Bellevue, WA; and Department of Neurology (DG), Boston University School of Medicine and Boston Medical Center, MA.
Dominic AdornoDepartment of Anesthesiology and Pain Medicine (AVL, MJS), Harborview Medical Center, University of Washington; Neurocritical Service (AVL, SW, MJS), Harborview Medical Center, University of Washington; Department of Neurological Surgery (AVL, MJS), Harborview Medical Center, University of Washington; Department of Neurology (SW), Harborview Medical Center, University of Washington, Seattle; LifeCenter Northwest (IB, DA, CW, KOC), Bellevue, WA; and Department of Neurology (DG), Boston University School of Medicine and Boston Medical Center, MA.
Candy WellsDepartment of Anesthesiology and Pain Medicine (AVL, MJS), Harborview Medical Center, University of Washington; Neurocritical Service (AVL, SW, MJS), Harborview Medical Center, University of Washington; Department of Neurological Surgery (AVL, MJS), Harborview Medical Center, University of Washington; Department of Neurology (SW), Harborview Medical Center, University of Washington, Seattle; LifeCenter Northwest (IB, DA, CW, KOC), Bellevue, WA; and Department of Neurology (DG), Boston University School of Medicine and Boston Medical Center, MA.
Kevin O'ConnorDepartment of Anesthesiology and Pain Medicine (AVL, MJS), Harborview Medical Center, University of Washington; Neurocritical Service (AVL, SW, MJS), Harborview Medical Center, University of Washington; Department of Neurological Surgery (AVL, MJS), Harborview Medical Center, University of Washington; Department of Neurology (SW), Harborview Medical Center, University of Washington, Seattle; LifeCenter Northwest (IB, DA, CW, KOC), Bellevue, WA; and Department of Neurology (DG), Boston University School of Medicine and Boston Medical Center, MA.
David GreerDepartment of Anesthesiology and Pain Medicine (AVL, MJS), Harborview Medical Center, University of Washington; Neurocritical Service (AVL, SW, MJS), Harborview Medical Center, University of Washington; Department of Neurological Surgery (AVL, MJS), Harborview Medical Center, University of Washington; Department of Neurology (SW), Harborview Medical Center, University of Washington, Seattle; LifeCenter Northwest (IB, DA, CW, KOC), Bellevue, WA; and Department of Neurology (DG), Boston University School of Medicine and Boston Medical Center, MA.
Michael J SouterDepartment of Anesthesiology and Pain Medicine (AVL, MJS), Harborview Medical Center, University of Washington; Neurocritical Service (AVL, SW, MJS), Harborview Medical Center, University of Washington; Department of Neurological Surgery (AVL, MJS), Harborview Medical Center, University of Washington; Department of Neurology (SW), Harborview Medical Center, University of Washington, Seattle; LifeCenter Northwest (IB, DA, CW, KOC), Bellevue, WA; and Department of Neurology (DG), Boston University School of Medicine and Boston Medical Center, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: To examine the verification of a referring hospital's practice of determining death by neurologic criteria (DNC) by an organ procurement organization (OPO) pursuant to the Center for Medicaid and Medicare Services rule §486.344(b). Methods: In this retrospective cohort study, we examined prevalence and factors associated with deviations from acceptable DNC standards, the performance of additional ancillary testing requested by the OPO, resolution of concerns about deviations between referring hospitals and the OPO, and interactions between referring hospitals and the OPO. Results: The OPO reviewed DNC processes for 645 adult potential organ donors from 64 referral hospitals. Concerns about practice deviations from acceptable standards were identified by the OPO's medical director (also a practicing neurointensivist) on call in 19% (n = 120) and were related to clinical prerequisites (27.2%, n = 49), clinical examination (23.9%, n = 67), and apnea testing (25.3%, n = 97). The top 3 concerns were apnea test results not meeting PCO Discussion: Ongoing review of institutional DNC standards and adherence to those standards is an urgent unmet need. Both referring hospitals and OPOs jointly carry responsibility for preventing errors in DNC leading up to organ recovery.

Identifiers

PMID36380895
PMCPMC9647811

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.