Evidence map›Paper›PMID 36380848›Full record

ArticleJAMIA open2022

Critical assessment of transformer-based AI models for German clinical notes.

Manuel Lentzen, Sumit Madan, Vanessa Lage-Rupprecht, Lisa Kühnel, Juliane Fluck, Marc Jacobs, Mirja Mittermaier, Martin Witzenrath, Peter Brunecker, Martin Hofmann-Apitius and 2 more

Abstract read
In one paragraph

Article in JAMIA open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Transformer models in biomedicine.BMC medical informatics and decision making · 2024
    Review
  13. Potential of Large Language Models in Health Care: Delphi Study.Journal of medical Internet research · 2024
    Article
  14. Rethinking Human-AI Collaboration in Complex Medical Decision Making: A Case Study in Sepsis Diagnosis.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2024
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Manuel LentzenDepartment of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Schloss Birlinghoven, Sankt Augustin, Germany.ORCID https://orcid.org/0000-0002-1344-4132
Sumit MadanDepartment of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Schloss Birlinghoven, Sankt Augustin, Germany.ORCID https://orcid.org/0000-0001-9970-4144
Vanessa Lage-RupprechtDepartment of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Schloss Birlinghoven, Sankt Augustin, Germany.
Lisa KühnelKnowledge Management, ZB MED - Information Centre for Life Sciences, Cologne, Germany.ORCID https://orcid.org/0000-0002-6356-6760
Juliane FluckKnowledge Management, ZB MED - Information Centre for Life Sciences, Cologne, Germany.ORCID https://orcid.org/0000-0003-1379-7023
Marc JacobsDepartment of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Schloss Birlinghoven, Sankt Augustin, Germany.ORCID https://orcid.org/0000-0003-4153-3930
Mirja MittermaierDepartment of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Martin WitzenrathDepartment of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Peter BruneckerBerlin Institute of Health at Charité - Universitätsmedizin Berlin, Core Facility Research IT, Berlin, Germany.
Martin Hofmann-ApitiusDepartment of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Schloss Birlinghoven, Sankt Augustin, Germany.ORCID https://orcid.org/0000-0001-9012-6720
Joachim WeberBerlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Holger FröhlichDepartment of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Schloss Birlinghoven, Sankt Augustin, Germany.ORCID https://orcid.org/0000-0002-5328-1243

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Healthcare data such as clinical notes are primarily recorded in an unstructured manner. If adequately translated into structured data, they can be utilized for health economics and set the groundwork for better individualized patient care. To structure clinical notes, deep-learning methods, particularly transformer-based models like Materials and Methods: We used 8 transformer-based models and pre-trained 3 new models on a newly generated biomedical corpus, and systematically compared them with each other. We annotated a new dataset of clinical notes and used it with 4 other corpora (BRONCO150, CLEF eHealth 2019 Task 1, GGPONC, and JSynCC) to perform named entity recognition (NER) and document classification tasks. Results: General-purpose language models can be used effectively for biomedical and clinical natural language processing (NLP) tasks, still, our newly trained BioGottBERT model outperformed GottBERT on both clinical NER tasks. However, training new biomedical models from scratch proved ineffective. Discussion: The domain-adaptation strategy's potential is currently limited due to a lack of pre-training data. Since general-purpose language models are only marginally inferior to domain-specific models, both options are suitable for developing German-language biomedical applications. Conclusion: General-purpose language models perform remarkably well on biomedical and clinical NLP tasks. If larger corpora become available in the future, domain-adapting these models may improve performances.

Indexed as

clinical concept extractionnatural language processingtransformer-based models

Identifiers

PMID36380848
PMCPMC9663939

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.