ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2022
When Brugada syndrome is at risk of sudden death: clinical and anatomical aspects.
Article in European heart journal supplements : journal of the European Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Assessment of Sudden Cardiac Death Risk in Pediatric Primary Electrical Disorders: A Comprehensive Overview.Diagnostics (Basel, Switzerland) · 2023Review
- Evaluation of a new treadmill exercise protocol to unmask type 1 Brugada electrocardiographic pattern: can we improve diagnostic yield?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Functional Characterisation of the RareInternational journal of molecular sciences · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current prognostic stratification of asymptomatic patients with Brugada syndrome is suboptimal. The so-called 'Brugada burden' concept is certainly emerging: the more extensive are the electrocardiographic alterations of the syndrome in space (peripheral as well as precordial derivations) and in time (persistence in the follow-up of electrocardiographic alterations), the greater the probability of arrhythmic events. Numerous clinical and electrocardiographic markers have been considered risk factors, but none of them alone is able to guide the choice of whether or not to implant a defibrillator, the only therapy so far proved effective in preventing SD (sudden death) in these patients. The prognostic value of the electrophysiology study also gradually decreased over time. Therapeutic decisions must therefore be taken, at the moment, considering a large number of variables, possibly included in risk scores to be validated prospectively and in large series. Magnetic resonance and the study of electro-anatomical alterations of the right ventricular outflow tract will most likely improve our prognostic stratification capacity in the future.
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Registered trials
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