Evidence map›Paper›PMID 36380739›Full record

SynthesisRenal failure2022

Impact of acute kidney injury on the risk of mortality in patients with cirrhosis: a systematic review and meta-analysis.

Yunfeng Ning, Xiaoyue Zou, Jing Xu, Xiao Wang, Min Ding, Hulin Lu

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
  9. The Renin-Angiotensin System in Liver Disease.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yunfeng NingDepartment of Nephropathy, First Affiliated Hospital, Huzhou Teachers College, the First People's Hospital of Huzhou, Huzhou, China.
Xiaoyue ZouDepartment of Emergency ICU, First Affiliated Hospital, Huzhou Teachers College, the First People's Hospital of Huzhou, Huzhou, China.
Jing XuDepartment of Nephropathy, First Affiliated Hospital, Huzhou Teachers College, the First People's Hospital of Huzhou, Huzhou, China.
Xiao WangDepartment of Nephropathy, First Affiliated Hospital, Huzhou Teachers College, the First People's Hospital of Huzhou, Huzhou, China.
Min DingDepartment of Nephropathy, First Affiliated Hospital, Huzhou Teachers College, the First People's Hospital of Huzhou, Huzhou, China.
Hulin LuDepartment of Nephropathy, First Affiliated Hospital, Huzhou Teachers College, the First People's Hospital of Huzhou, Huzhou, China.
Huzhou University · CNThird People's Hospital of Huzhou · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the risk of mortality in patients with cirrhosis with and without the associated acute kidney injury (AKI).

methodsWe performed a systematic search in the PubMed, Embase, and Scopus databases for observational studies that were done on patients with cirrhosis. Eligible studies reported AKI in patients with cirrhosis and compared mortality among patients with and without AKI. We used a random-effects model, using STATA version 16.0, for deriving pooled effect sizes that were reported as odds ratio (OR) with 95% confidence intervals (CIs).

resultsThirty-two studies were included. In patients with cirrhosis, AKI was significantly associated with higher in-hospital mortality (OR 5.92), and mortality at 30 days (OR 4.78), 90 days (OR 4.34), and at 1 year follow-up (OR 4.82) compared to patients without AKI.

conclusionsAKI is associated with an increased risk of mortality in patients with cirrhosis. Careful monitoring to identify the development of AKI and early prompt management is necessary.

Indexed as

Acute Kidney InjuryHumansLiver CirrhosisAcute kidney injurycomplicationsdecompensated cirrhosismeta-analysismortalityterlipressin

Identifiers

PMID36380739
PMCPMC9673785
OpenAlexW4309332183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.