ArticleJournal of hospital medicine2022
Antibiotic use and outcomes among children hospitalized with suspected pneumonia.
Article in Journal of hospital medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Differences in antibiotic treatment for children hospitalized with pneumonia.Journal of hospital medicine · 2026Article
- Children Hospitalized With Pneumonia Who Complete Oral Antibiotic Treatment Without Complications.Hospital pediatrics · 2026Article
- Guideline-Concordant Antibiotic Use in Children With Community-Acquired Pneumonia.Hospital pediatrics · 2025Article
- Association between initial antibiotic route and outcomes for children hospitalized with pneumonia.Journal of hospital medicine · 2025Article
- How to Interact With Interactions: What Clinicians Should Know About Statistical Interactions.Hospital pediatrics · 2023Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundAlthough viral etiologies predominate, antibiotics are frequently prescribed for community-acquired pneumonia (CAP).
objectiveWe evaluated the association between antibiotic use and outcomes among children hospitalized with suspected CAP. DESIGNS, SETTINGS AND
participantsWe performed a secondary analysis of a prospective cohort of children hospitalized with suspected CAP.
interventionThe exposure was the receipt of antibiotics in the emergency department (ED). MAIN OUTCOME AND MEASURES: Clinical outcomes included length of stay (LOS), care escalation, postdischarge treatment failure, 30-day ED revisit, and quality-of-life (QoL) measures from a follow-up survey 7-15 days post discharge. To minimize confounding by indication (e.g., radiographic CAP), we performed inverse probability treatment weighting with propensity analyses.
resultsAmong 523 children, 66% were <5 years, 88% were febrile, 55% had radiographic CAP, and 55% received ED antibiotics. The median LOS was 41 h (IQR: 25, 54). After propensity analyses, there were no differences in LOS, escalated care, treatment failure, or revisits between children who received antibiotics and those who did not. Seventy-one percent of patients completed follow-up surveys after discharge. Among 16% of patients with fevers after discharge, the median fever duration was 2 days, and those who received antibiotics had a 37% decrease in the mean number of days with fever (95% confidence interval: 20% and 51%). We found no statistical differences in other QoL measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.