Evidence map›Paper›PMID 36380200›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2023

Accuracy of screening strategies for masked hypertension: a large-scale nationwide study based on home blood pressure monitoring.

Marco A M Alves, Audes D M Feitosa, Marco A Mota-Gomes, Annelise M G Paiva, Weimar S Barroso, Roberto D Miranda, Eduardo C D Barbosa, Andréa A Brandão, Paulo G S Diniz, Otavio Berwanger and 4 more

Abstract read
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In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Guideline
  2. Brazilian Guidelines of Hypertension - 2025.Arquivos brasileiros de cardiologia · 2025
    Article
  3. Article
  4. Optimal timing for post-dialysis blood pressure measurement: relationship with home blood pressure monitoring.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  5. Article
  6. Article
  7. 2023 update and perspectives.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  8. Masked hypertension: how not to miss an even more silent killer.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 2 countries.

Marco A M AlvesLaboratory of Immunopathology Keizo Asami, Federal University of Pernambuco, Recife, PE, Brazil.
Audes D M FeitosaLaboratory of Immunopathology Keizo Asami, Federal University of Pernambuco, Recife, PE, Brazil.
Marco A Mota-GomesCESMAC University Center/Heart Hospital of Alagoas, Maceió, AL, Brazil.
Annelise M G PaivaCESMAC University Center/Heart Hospital of Alagoas, Maceió, AL, Brazil.
Weimar S BarrosoHypertension League, Cardiovascular Section, Federal University of Goiás, Goiânia, GO, Brazil.
Roberto D MirandaCardiovascular Section, Geriatrics Division, Paulista School of Medicine, Federal University of São Paulo, São Paulo, SP, Brazil.
Eduardo C D BarbosaDepartment of Hypertension and Cardiometabolism, São Francisco Hospital - Santa Casa de Porto Alegre, Porto Alegre, Brazil.
Andréa A BrandãoSchool of Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Paulo G S DinizLaboratory of Immunopathology Keizo Asami, Federal University of Pernambuco, Recife, PE, Brazil.
Otavio BerwangerAcademic Research Organization (ARO), Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
José L Lima-FilhoLaboratory of Immunopathology Keizo Asami, Federal University of Pernambuco, Recife, PE, Brazil.
Andrei C SpositoDepartment of Internal Medicine, School of Medical Sciences, State University of Campinas, SP Paulo, Brazil.
Antonio CocaHypertension and Vascular Risk Unit, Department of Internal Medicine, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Wilson NadruzLaboratory of Immunopathology Keizo Asami, Federal University of Pernambuco, Recife, PE, Brazil. wilnj@fcm.unicamp.br.
Universidade Federal de Pernambuco · BRCentro Universitário Cesmac · BRUniversidade Estadual de Campinas (UNICAMP) · BRHospital Israelita Albert Einstein · BRSanta Casa Hospital · BRUniversidade do Estado do Rio de Janeiro · BRUniversidade Federal de Goiás · BRUniversidade Federal de São Paulo · BRUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compared the ability of guideline-proposed office blood pressure (OBP) screening thresholds [European Society of Hypertension (ESH) guidelines: 130/85 mmHg for individuals with an OBP < 140/90 mmHg; American College of Cardiology/American Heart Association (ACC/AHA) guidelines: 120/75 mmHg for individuals with an OBP < 130/80 mmHg] and novel screening scores to identify normotensive individuals at high risk of having masked hypertension (MH) in an office setting. We cross-sectionally evaluated untreated participants with an OBP < 140/90 mmHg (n = 22,266) and an OBP < 130/80 mmHg (n = 10,005) who underwent home blood pressure monitoring (HBPM) (derivation cohort) from 686 Brazilian sites. MH was defined according to criteria suggested by the ESH (OBP < 140/90 mmHg; HBPM ≥ 135/85 mmHg), Brazilian Society of Cardiology (BSC) (OBP < 140/90 mmHg; HBPM ≥ 130/80 mmHg) and ACC/AHA (OBP < 130/80 mmHg; HBPM ≥ 130/80 mmHg). Scores were generated from multivariable logistic regression coefficients between MH and clinical variables (OBP, age, sex, and BMI). Considering the ESH, BSC, and ACC/AHA criteria, 17.2%, 38.5%, and 21.2% of the participants had MH, respectively. Guideline-proposed OBP screening thresholds yielded area under curve (AUC) values of 0.640 (for ESH criteria), 0.641 (for BSC criteria), and 0.619 (for ACC/AHA criteria) for predicting MH, while scores presented as continuous variables or quartiles yielded AUC values of 0.700 and 0.688 (for ESH criteria), 0.720 and 0.709 (for BSC criteria), and 0.671 and 0.661 (for ACC/AHA criteria), respectively. Further analyses performed with alternative untreated participants (validation cohort; n = 2807 with an OBP < 140/90 mmHg; n = 1269 with an OBP < 130/80 mmHg) yielded similar AUC values. In conclusion, the accuracy of guideline-proposed OBP screening thresholds in identifying individuals at high risk of having MH in an office setting is limited and is inferior to that yielded by scores derived from simple clinical variables.

Indexed as

HypertensionMasked HypertensionBlood PressureBlood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryHumansUnited StatesGuidelinesHome blood pressureMasked hypertensionScreening

Identifiers

PMID36380200
OpenAlexW4309158432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.