Evidence map›Paper›PMID 36380188›Full record

ArticleScientific reports2022

Association between fractional amplitude of low-frequency fluctuation (fALFF) and facial emotion recognition ability in first-episode schizophrenia patients: a fMRI study.

Qijie Kuang, Sumiao Zhou, Haijing Li, Lin Mi, Yingjun Zheng, Shenglin She

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In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

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4citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Qijie Kuang *Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510370, People's Republic of China.
Sumiao Zhou *Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510370, People's Republic of China.
Haijing Li *Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510370, People's Republic of China.
Lin MiDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510370, People's Republic of China.
Yingjun ZhengDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510370, People's Republic of China. brainzheng@gzhmu.edu.cn.
Shenglin SheDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510370, People's Republic of China. shenglinshe@gzhmu.edu.cn.

Funding

the Planed Science and Technology Projects of Guangzhou 201904010267
6 · The paper itself

Abstract

It was still unclear that the correlation between the resting-state intrinsic activity in brain regions and facial emotion recognition (FER) ability in patients with first-episode schizophrenia (FSZ). Our aim was to analyse the correlation between the fractional amplitude of low-frequency fluctuation (fALFF) and FER ability in FSZ patients. A total of 28 patients with FSZ and 33 healthy controls (HCs) completed visual search tasks for FER ability. Regions of interest (ROIs) related to facial emotion were obtained from a previous meta-analysis. Pearson correlation analysis was performed to understand the correlation between fALFF and FER ability. Our results indicated that the patients performed worse than the HCs in the accuracy performances of happy FER and fearful FER. The previous meta-analysis results showed that the brain regions related to FER included the bilateral amygdala (AMY)/hippocampus (HIP), right fusiform gyrus (FFG), and right supplementary motor area (SMA). Partial correlation analysis showed that the fALFF of the right FFG was associated with high-load fearful FER accuracy (r = - 0.60, p = 0.004). Our study indicated that FER ability is correlated with resting-state intrinsic activity in brain regions related to facial emotion, which may provide a reference for the study of FER deficiency in schizophrenia.

Indexed as

Facial RecognitionSchizophreniaBrainBrain MappingHumansMagnetic Resonance Imaging

Identifiers

PMID36380188
PMCPMC9666540

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.