Evidence map›Paper›PMID 36380136›Full record

ArticleScientific reports2022

Neuroticism and adverse life events are important determinants in functional somatic disorders: the DanFunD study.

Marie Weinreich Petersen, Tina Birgitte Wisbech Carstensen, Lisbeth Frostholm, Kaare Bro Wellnitz, Eva Ørnbøl, Thomas Tandrup Lamm, Thomas Meinertz Dantoft, Lene Falgaard Eplov, Torben Jørgensen, Per Fink

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Marie Weinreich PetersenResearch Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Palle Juul Jensens Boulevard 11, 8200, Aarhus N, Denmark. mawept@rm.dk.
Tina Birgitte Wisbech CarstensenResearch Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Palle Juul Jensens Boulevard 11, 8200, Aarhus N, Denmark.
Lisbeth FrostholmResearch Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Palle Juul Jensens Boulevard 11, 8200, Aarhus N, Denmark.
Kaare Bro WellnitzResearch Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Palle Juul Jensens Boulevard 11, 8200, Aarhus N, Denmark.
Eva ØrnbølResearch Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Palle Juul Jensens Boulevard 11, 8200, Aarhus N, Denmark.
Thomas Tandrup LammResearch Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Palle Juul Jensens Boulevard 11, 8200, Aarhus N, Denmark.
Thomas Meinertz DantoftCenter for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Copenhagen, Denmark.
Lene Falgaard EplovCopenhagen Research Center for Mental Health, Mental Health Centre Copenhagen, The Capital Region of Denmark, Copenhagen, Denmark.
Torben JørgensenCenter for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Copenhagen, Denmark.
Per FinkResearch Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Palle Juul Jensens Boulevard 11, 8200, Aarhus N, Denmark.
Aarhus University Hospital · DKAarhus University · DKCapital Region of Denmark · DKFrederiksberg Hospital · DK

Funding

Lundbeckfonden R155-2013-14070TrygFonden 7-11-0213
6 · The paper itself

Abstract

Several psychological factors have been proposed to be associated with functional somatic disorders (FSD). However, large population-based studies investigating the importance of both personality and adverse life events (ALE) are sparse. This study aimed to investigate the association between FSD and neuroticism and the accumulated number of ALE, respectively. This cross-sectional study included a random sample of the adult Danish population (N = 7493). FSD were established by means of self-reported questionnaires and diagnostic interviews. Neuroticism was measured with the Danish version of the short-form NEO Personality Inventory. ALE were measured with the Danish version of the Cumulative Lifetime Adversity Measure. Strong positive associations were found between neuroticism and FSD, and ALE and questionnaire-based FSD. For interview-based FSD, strong positive associations were found for FSD, multi-organ type, and for the subtype of the general symptoms. The level of self-efficacy did not modify these associations, and no moderating effect of neuroticism and ALE in combination on the probability of having FSD was found. FSD were strongly associated with both neuroticism and the accumulated number of ALE, and these associations were not modified by self-efficacy. In combination, neuroticism and ALE did not have a moderating effect on the probability of having FSD.

Indexed as

PersonalityPersonality DisordersAdultCross-Sectional StudiesHumansNeuroticismSurveys and Questionnaires

Identifiers

PMID36380136
PMCPMC9666664
OpenAlexW4309437681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.