Evidence map›Paper›PMID 36380099›Full record

ArticleAesthetic plastic surgery2023

A Rare Case of BIA-ALCL Mass Associated with Mastectomy Skin Flap Erythema After Immunization with COVID-19.

Cristina Garusi, Eleonora De Antoni, Stefano Fiori, Anna Vanazzi, Stefano A Pileri

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Aesthetic plastic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Cristina GarusiDepartment of Plastic and Reconstructive Surgery, IEO European Institute of Oncology, Milan, Italy.
Eleonora De AntoniDepartment of Plastic and Reconstructive Surgery, AOVR Verona University Hospital, Piazzale Stefani 1, 37126, Verona, Italy. eleonoradeantoni@gmail.com.ORCID http://orcid.org/0000-0003-3546-4377
Stefano FioriHaematopathology Division, IEO European Institute of Oncology, Milan, Italy.
Anna VanazziClinical Haemato-Oncology, IEO European Institute of Oncology, Milan, Italy.
Stefano A PileriHaematopathology Division, IEO European Institute of Oncology, Milan, Italy.
European Institute of Oncology · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe immune response to breast implants after COVID-19 disease or COVID-19 vaccine administration includes acute inflammatory manifestations, capsular contracture and seroma. Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a very rare tumor in which numerous up-regulated pro-inflammatory immunological pathways activate a T cell lymphoproliferative disorder.

methodsThe first reported case of a BIA-ALCL hidden mass clinically manifesting with inflammatory signs after SARS-CoV-2 infection and vaccinations is here described.

resultsComplete capsulectomy and adjuvant chemotherapy were performed and immediately after the surgical procedure local inflammatory signs disappeared; no evidence of disease was present 1 year later.

conclusionsImmunological stimulation by COVID-19 disease and vaccines may highlight some rare clinical manifestations of BIA-ALCL; persistent inflammatory symptomatology over breast implants should be investigated using second-level imaging. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Breast ImplantationBreast ImplantsBreast NeoplasmsCOVID-19Lymphoma, Large-Cell, AnaplasticCOVID-19 VaccinesFemaleHumansImmunizationMastectomySARS-CoV-2VaccinationCOVID-19 VaccinesBIA-ALCLCOVID-19ErythemaInflammatory signsTenderness

Identifiers

PMID36380099
PMCPMC9666973
OpenAlexW4309083381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.