ArticlePediatric research2023
Left ventricular function before and after percutaneous patent ductus arteriosus closure in preterm infants.
Article in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Early drug treatment in preterm patients with large patent ductus arteriosus at 28 weeks or less gestational age: systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2025Pooled it
- Targeted Neonatal Echocardiography in Neonatal Patent Ductus Arteriosus Management: A Systematic Review of Clinical Utility and Outcomes.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Left ventricular diastolic dysfunction in preterm infants with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Identifying Factors Associated with Prolonged Postoperative Mechanical Ventilation in Preterm Infants Undergoing Patent Ductus Arteriosus Ligation Using Machine Learning and SHAP Analysis: A Large-Sample Single-Center Retrospective Analysis.Journal of clinical medicine · 2026Article
- Diastolic function in newborn infants: understanding pathophysiology, diagnosis and clinical relevance.Pediatric research · 2026Review
- Biventricular adaptation after patent ductus arteriosus ligation.Pediatric research · 2026Article
- Changes in cardiorespiratory status after transcatheter patent ductus arteriosus closure.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Effect of Transcatheter Closure of the Ductus Arteriosus on Right Ventricular Function in Preterm Neonates.Pediatric cardiology · 2026Article
- Echocardiographic Predictors and Incidence of Left Ventricular Dysfunction Following Transcatheter Patent Ductus Arteriosus Closure in Extremely Premature Infants.Pediatric cardiology · 2026Article
- Hemodynamic evaluation following ductal closure and association with IVH in premature infants born at 22-23weeks gestation.Frontiers in pediatrics · 2026Article
- Article
- [Risk factors for cardiopulmonary dysfunction after ligation of hemodynamically significant patent ductus arteriosus in preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Who Still Gets Ligated? Reasons for Persistence of Surgical Ligation of the Patent Ductus Arteriosus Following Availability of Transcatheter Device Occlusion for Premature Neonates.Journal of cardiovascular development and disease · 2024Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDefinitive closure of the patent ductus arteriosus (PDA) is associated with significant changes in the loading conditions of the left ventricle (LV), which may lead to cardiovascular and respiratory instability. The objective of the study was to evaluate targeted neonatal echocardiography (TnECHO) characteristics and the clinical course of preterm infants ≤2 kg undergoing percutaneous PDA closure.
methodsRetrospective cohort study of prospectively acquired pre- and post-closure TnECHOs to assess hemodynamic changes. Cardiorespiratory parameters in the first 24 h following PDA closure were also evaluated.
resultsFifty patients were included with a mean age of 30.6 ± 9.6 days and weight of 1188 ± 280 g. LV global longitudinal strain decreased from -20.6 ± 2.6 to -14.9 ± 2.9% (p < 0.001) after 1 h. There was a decrease in LV volume loading, left ventricular output, LV systolic and diastolic parameters. Cardiorespiratory instability occurred in 24 (48%) [oxygenation failure in 44%] but systolic hypotension and/or need for cardiovascular medications was only seen in 6 (12%). Patients with instability had worse baseline respiratory severity score and lower post-closure early diastolic strain rates.
conclusionsPercutaneous PDA closure leads to a reduction in echocardiography markers of LV systolic/diastolic function. Post-closure cardiorespiratory instability is characterized primarily by oxygenation failure and may relate to impaired diastolic performance. IMPACT: Percutaneous patent ductus arteriosus closure leads to a reduction in echocardiography markers of left ventricular volume loading, cardiac output, and left ventricular systolic/diastolic function. Post-procedural cardiorespiratory instability is characterized primarily by oxygenation failure. Post-procedural cardiorespiratory instability may relate to impaired diastolic performance.
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