Evidence map›Paper›PMID 36379996›Full record

ArticleScientific reports2022

Adverse events following administration of COVID-19 vaccines in Saudi Arabia.

Saleh Alqahtani, Hani Jokhdar, Jaffar A Al-Tawfiq, Salah Al-Otaibi, Abdullah Assiri, Sami Almudarra, Khaled Alabdulkareem, Alhan Haji

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Saleh AlqahtaniDepartment of Medicine, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Hani JokhdarDeputyship of Public Health, Ministry of Health, Riyadh, Saudi Arabia.
Jaffar A Al-TawfiqSpecialty Internal Medicine and Quality Patient Safety Department, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Salah Al-OtaibiDepartment of Anesthesia, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Abdullah AssiriAssisting Deputyship for Preventive Health, Ministry of Health, Riyadh, Saudi Arabia.
Sami AlmudarraAssisting Deputyship for Preventive Health, Ministry of Health, Riyadh, Saudi Arabia.
Khaled AlabdulkareemAssisting Deputyship for Primary Health Care, Ministry of Health, Riyadh, 11176, Saudi Arabia.
Alhan HajiAssisting Deputyship for Primary Health Care, Ministry of Health, Riyadh, 11176, Saudi Arabia. Alhan.haji@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies investigated the frequency of different adverse events of COVID-19 vaccines. However, this study compares these adverse events between the two main COVID-19 vaccines used in Saudi Arabia (Pfizer-BioNTech and Oxford-AstraZeneca) using telemedicine technology. A cross-sectional study was conducted among 958 individuals, 7 days after receiving either Pfizer-BioNTech or Oxford-AstraZeneca vaccines during June 2021. Immediate adverse events were reported by 1.04% and 2.09% for Pfizer-BioNTech and Oxford-AstraZeneca vaccines, respectively, with no serious events. Recipients of Pfizer-BioNTech vaccine had a higher percentage of local adverse events (24.8% versus 9.8% in AstraZeneca vaccine). The most common reported systemic adverse events in both vaccines respectively were general fatigue (23.1% and 25.1%), fever (18.5% and 27.2%), myalgia (20.6% and 20.3%), and headache (15.2% and 17.2%). No significant difference was recorded between both vaccines regarding overall systemic adverse events; however, they were more frequent following the first dose of AstraZeneca vaccine compared to Pfizer-BioNTech vaccine, while the reverse was observed for the second dose. Adverse events were more frequent in females and younger age groups for both vaccines. Most of systemic and local adverse events were mild in nature. Further cohort studies are recommended to investigate the long-term adverse events of COVID-19 vaccines.

Indexed as

COVID-19COVID-19 VaccinesVaccinesCross-Sectional StudiesFemaleHumansSaudi ArabiaCOVID-19 VaccinesVaccines

Identifiers

PMID36379996
PMCPMC9664034

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.