Evidence map›Paper›PMID 36379610›Full record

ArticleJournal of Zhejiang University. Science. B2022

Clinical and immune response characteristics among vaccinated persons infected with SARS-CoV-2 delta variant: a retrospective study.

Cunjin Wang, Yong Li, Yuchen Pan, Luojing Zhou, Xi Zhang, Yan Wei, Fang Guo, Yusheng Shu, Ju Gao

Open access · bronzeAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Cunjin WangDepartment of Anesthesiology, Northern Jiangsu People's Hospital, Yangzhou 225001, China.
Yong LiDepartment of Anesthesiology, Northern Jiangsu People's Hospital, Yangzhou 225001, China.
Yuchen PanDepartment of Neurology, Jiangsu Provincial Corps Hospital, Chinese People's Armed Police Force, Yangzhou 225000, China.
Luojing ZhouClinical Medical College, Yangzhou University, Yangzhou 225001, China.
Xi ZhangClinical Medical College, Yangzhou University, Yangzhou 225001, China.
Yan WeiDepartment of Anesthesiology, Northern Jiangsu People's Hospital, Yangzhou 225001, China.
Fang GuoDepartment of Anesthesiology, Northern Jiangsu People's Hospital, Yangzhou 225001, China.
Yusheng ShuClinical Medical College, Yangzhou University, Yangzhou 225001, China. shuyusheng65@163.com.
Ju GaoDepartment of Anesthesiology, Northern Jiangsu People's Hospital, Yangzhou 225001, China. gaoju_003@163.com.
Northern Jiangsu People's Hospital · CNJiangSu Armed Police General Hospital · CNYangzhou University · CN

Funding

the Jiangsu Association for Science and Technology Young Scientific and Technological Talents Support Project 2021-008the Jiangsu Province "333" High-level Talents Training Project 2022-3-6-146the National Natural Science Foundation of China 82171207 and 82172190the Yangzhou Science and Technology Plan Project YZ2021088 and YZ2021148
6 · The paper itself

Abstract

objectivesThis study aimed to observe the clinical and immune response characteristics of vaccinated persons infected with the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Yangzhou, China.

methodsWe extracted the medical data of 129 patients with delta-variant infection who were admitted to Northern Jiangsu People's Hospital (Yangzhou, China) between August and September, 2021. The patients were grouped according to the number of vaccine doses received into an unvaccinated group: a one-dose group and a two-dose group. The vaccine used was SARS-CoV-2-inactivated vaccine developed by Sinovac. We retrospectively analyzed the patients' epidemiological, clinical, laboratory, and imaging data.

resultsAlmost all patients with delta-variant infection in Yangzhou were elderly, and patients with severe/critical illness were over 70 years of age. The rates of severe/critical illness (

conclusionsTwo doses of the SARS-CoV-2-inactivated vaccine were highly effective at limiting symptomatic disease and reducing immune response, while a single dose did not seem to be effective.

Indexed as

COVID-19COVID-19 VaccinesAgedAged, 80 and overCritical IllnessHumansImmunityRetrospective StudiesSARS-CoV-2Vaccines, InactivatedViral VaccinesCOVID-19 VaccinesVaccines, InactivatedViral VaccinesDelta variantHospitalizationImmune responseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Vaccine

Identifiers

PMID36379610
PMCPMC9676093
OpenAlexW4309654134

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.