Evidence map›Paper›PMID 36379607›Full record

ArticleTrends in hearing

The Relationship Between Interaural Insertion-Depth Differences, Scalar Location, and Interaural Time-Difference Processing in Adult Bilateral Cochlear-Implant Listeners.

Miranda Cleary, Joshua G W Bernstein, Olga A Stakhovskaya, Jack Noble, Elizabeth Kolberg, Kenneth K Jensen, Michael Hoa, Hung Jeffrey Kim, Matthew J Goupell

Open access · goldAbstract read
In one paragraph

Article in Trends in hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. A systematic review of electrode array scalar dislocation after cochlear implant surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Pulse timing dominates binaural hearing with cochlear implants.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Miranda ClearyDepartment of Hearing and Speech Sciences, 1068University of Maryland, College Park, MD, USA.
Joshua G W BernsteinNational Military Audiology and Speech Pathology Center, 8395Walter Reed National Military Medical Center, Bethesda, MD, USA.
Olga A StakhovskayaDepartment of Hearing and Speech Sciences, 1068University of Maryland, College Park, MD, USA.
Jack NobleDepartment of Electrical Engineering and Computer Science, 5718Vanderbilt University, Nashville, TN, USA.
Elizabeth KolbergDepartment of Hearing and Speech Sciences, 1068University of Maryland, College Park, MD, USA.
Kenneth K JensenNational Military Audiology and Speech Pathology Center, 8395Walter Reed National Military Medical Center, Bethesda, MD, USA.
Michael HoaDepartment of Otolaryngology-Head and Neck Surgery, 12231Georgetown University Medical Center, Washington, DC, USA.
Hung Jeffrey KimDepartment of Otolaryngology-Head and Neck Surgery, 12231Georgetown University Medical Center, Washington, DC, USA.
Matthew J GoupellDepartment of Hearing and Speech Sciences, 1068University of Maryland, College Park, MD, USA.ORCID 0000-0003-2662-3057
University of Maryland, College Park · USGeorgetown University · USWalter Reed National Military Medical Center · USVanderbilt University · US

Funding

Model-based Cochlear Implant ProgrammingR01DC014037 · NIDCD · VANDERBILT UNIVERSITY · PI NOBLE, JACK · 2014 to 2024
$5.0M
Computer-assisted, image-guided programming of Cochlear ImplantsR01DC014462 · NIDCD · VANDERBILT UNIVERSITY · PI DAWANT, BENOIT M. · 2016 to 2020
$2.9M
Optimizing Bilateral and Single-Sided Deafness Cochlear Implants for Functioning in Complex Auditory EnvironmentsR01DC015798 · NIDCD · UNIV OF MARYLAND, COLLEGE PARK · PI BERNSTEIN, JOSHUA GARY, GOUPELL, MATTHEW J. · 2017 to 2021
$2.0M
NIDCD NIH HHS R01 DC014037NIDCD NIH HHS R01 DC014462NIDCD NIH HHS R01 DC015798
6 · The paper itself

Abstract

Sensitivity to interaural time differences (ITDs) in acoustic hearing involves comparison of interaurally frequency-matched inputs. Bilateral cochlear-implant arrays are, however, only approximately aligned in angular insertion depth and scalar location across the cochleae. Interaural place-of-stimulation mismatch therefore has the potential to impact binaural perception. ITD left-right discrimination thresholds were examined in 23 postlingually-deafened adult bilateral cochlear-implant listeners, using low-rate constant-amplitude pulse trains presented via direct stimulation to single electrodes in each ear. Angular insertion depth and scalar location measured from computed-tomography (CT) scans were used to quantify interaural mismatch, and their association with binaural performance was assessed. Number-matched electrodes displayed a median interaural insertion-depth mismatch of 18° and generally yielded best or near-best ITD discrimination thresholds. Two listeners whose discrimination thresholds did not show this pattern were confirmed via CT to have atypical array placement. Listeners with more number-matched electrode pairs located in the scala tympani displayed better thresholds than listeners with fewer such pairs. ITD tuning curves as a function of interaural electrode separation were broad; bandwidths at twice the threshold minimum averaged 10.5 electrodes (equivalent to 5.9 mm for a Cochlear-brand pre-curved array). Larger angular insertion-depth differences were associated with wider bandwidths. Wide ITD tuning curve bandwidths appear to be a product of both monopolar stimulation and angular insertion-depth mismatch. Cases of good ITD sensitivity with very wide bandwidths suggest that precise matching of insertion depth is not critical for discrimination thresholds. Further prioritizing scala tympani location at implantation should, however, benefit ITD sensitivity.

Indexed as

Cochlear ImplantationCochlear ImplantsSound LocalizationAcoustic StimulationAdultHearingHearing TestsHumansbinaural hearingcochlear implantationcomputed-tomography scanshearing loss

Identifiers

PMID36379607
PMCPMC9669699
OpenAlexW4309409150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.