Evidence map›Paper›PMID 36379539›Full record

ArticleSaudi medical journal2022

Clinical significance of CA-125 in elderly patients with active pulmonary tuberculosis: A retrospective study.

Ping Zhao, Liang Chen, Ze Q Xie, Ji Y Jian, Pan P Sun

Open access · diamondFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Establishing a clinical tool to predict acute kidney injury in pulmonary tuberculosis: insights from a large-scale retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ping ZhaoFrom the Department of Clinical Laboratory (Zhao, Chen, Xie, Jian, Sun), Beijing Shijitan Hospital, Capital Medical University; and from Beijing Key Laboratory of Urinary Cellular Molecular Diagnostics (Zhao, Chen, Xie, Jian, Sun), Beijing, China.
Liang ChenFrom the Department of Clinical Laboratory (Zhao, Chen, Xie, Jian, Sun), Beijing Shijitan Hospital, Capital Medical University; and from Beijing Key Laboratory of Urinary Cellular Molecular Diagnostics (Zhao, Chen, Xie, Jian, Sun), Beijing, China.
Ze Q XieFrom the Department of Clinical Laboratory (Zhao, Chen, Xie, Jian, Sun), Beijing Shijitan Hospital, Capital Medical University; and from Beijing Key Laboratory of Urinary Cellular Molecular Diagnostics (Zhao, Chen, Xie, Jian, Sun), Beijing, China.
Ji Y JianFrom the Department of Clinical Laboratory (Zhao, Chen, Xie, Jian, Sun), Beijing Shijitan Hospital, Capital Medical University; and from Beijing Key Laboratory of Urinary Cellular Molecular Diagnostics (Zhao, Chen, Xie, Jian, Sun), Beijing, China.
Pan P SunFrom the Department of Clinical Laboratory (Zhao, Chen, Xie, Jian, Sun), Beijing Shijitan Hospital, Capital Medical University; and from Beijing Key Laboratory of Urinary Cellular Molecular Diagnostics (Zhao, Chen, Xie, Jian, Sun), Beijing, China.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the clinical significance of serum CA-125 levels in elderly patients with pulmonary tuberculosis (PTB).

methodsWe retrospectively analyzed 1613 participants-patients (aged ≥60 years) admitted to the Beijing Shijitan Hospital, Beijing, China from February 2015 to January 2021 and healthy participants, divided into 4 groups: PTB (group 1), pulmonary malignancies (group 2), pulmonary non-malignant diseases (group 3), and healthy participants (group 4). Data concerning demographics, physical examination findings, computed tomography, histopathological examination, and laboratory tests for

resultsThere were 720 healthy individuals and 893 patients in the study. The median levels and abnormal rates of CA-125 in groups 1 (42.5, 57.3%) and 2 (34.4, 49.5%) were higher than those in groups 3 (21.1, 29.2%) and 4 (8.6, 0.4%) (

conclusionAlthough elevated CA-125 levels may serve as a potential marker for diagnosing PTB in the elderly, they are affected by multiple factors, including serous effusion. Hence, caution is warranted while using this marker.

Indexed as

Lung DiseasesMycobacterium tuberculosisTuberculosisTuberculosis, PulmonaryAgedBiomarkersHumansLungRetrospective StudiesBiomarkersantigenCA-125effusionelderlypleuralpulmonarytuberculosis

Identifiers

PMID36379539
PMCPMC10043917
OpenAlexW4309360390

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read8
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.