Evidence map›Paper›PMID 36379530›Full record

Trial reportSaudi medical journal2022

The role of intra-articular injection of autologous platelet-rich plasma versus corticosteroids in the treatment of synovitis in lumbar facet joint disease.

Shahdan Y Kotb, Nahed M Sherif, Hala A Saleh, Sahar F Ahmed, Hossam M Sakr, Mohamed O Taeimah

Registry-linked trialOpen access · diamondFull text readRandomized Controlled Trial
In one paragraph

Trial report in Saudi medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04860531 (The Role of Intra-articular Injection of Autologous Platelet Rich Plasma Versus Corticosteriods in Treatment of Synovitis in Lumbar Facet Joint Disease), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04860531 phase3completednot on this map

The Role of Intra-articular Injection of Autologous Platelet Rich Plasma Versus Corticosteriods in Treatment of Synovitis in Lumbar Facet Joint Disease

TypeinterventionalSponsorAin Shams UniversityRan2019 to 2021Enrolled30ConditionsLumbar Facet Joint SyndromeArmsLumbar Facet Joints intra-articular injection with Platelet Rich Plasma, Lumbar Facet Joints intra-articular injection with a mixture of 0.5% lidocaine and 5mg/ml of betamethasone
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Overview of Available Treatments and Their Limitations for Hypertrophic Facet Joints-A Systematic Review of the Literature.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Lumbar Facet Joint Disease: What, Why, and When?Life (Basel, Switzerland) · 2024
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shahdan Y KotbFrom the Department of Physical Medicine, Rheumatology and Rehabilitation (Kotb, Sherif, Saleh, Ahmed); from the Department of Radiodiagnosis (Sakr); and from the Department of Anesthesiology, Intensive Care and Pain Management (Taeimah), Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Nahed M SherifFrom the Department of Physical Medicine, Rheumatology and Rehabilitation (Kotb, Sherif, Saleh, Ahmed); from the Department of Radiodiagnosis (Sakr); and from the Department of Anesthesiology, Intensive Care and Pain Management (Taeimah), Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Hala A SalehFrom the Department of Physical Medicine, Rheumatology and Rehabilitation (Kotb, Sherif, Saleh, Ahmed); from the Department of Radiodiagnosis (Sakr); and from the Department of Anesthesiology, Intensive Care and Pain Management (Taeimah), Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Sahar F AhmedFrom the Department of Physical Medicine, Rheumatology and Rehabilitation (Kotb, Sherif, Saleh, Ahmed); from the Department of Radiodiagnosis (Sakr); and from the Department of Anesthesiology, Intensive Care and Pain Management (Taeimah), Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Hossam M SakrFrom the Department of Physical Medicine, Rheumatology and Rehabilitation (Kotb, Sherif, Saleh, Ahmed); from the Department of Radiodiagnosis (Sakr); and from the Department of Anesthesiology, Intensive Care and Pain Management (Taeimah), Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Mohamed O TaeimahFrom the Department of Physical Medicine, Rheumatology and Rehabilitation (Kotb, Sherif, Saleh, Ahmed); from the Department of Radiodiagnosis (Sakr); and from the Department of Anesthesiology, Intensive Care and Pain Management (Taeimah), Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Ain Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the efficacy between platelet-rich plasma (PRP) and corticosteroids (CS) in improving magnetic resonance imaging (MRI)-detected synovitis in correlation with clinical complaints among patients with lumbar facet joint (FJ) disease.

methodsThis study was carried out at Eldemerdash Hospital, Cairo, Egypt between September 2019 and January 2021. A prospective, randomized, comparative, single blinded study included 30 patients with lumbar FJ disease, divided into 2 equal groups, received PRP and CS injections. Patients were comparatively assessed before and after the intervention according to number of tender lumbar FJs, maximum active lumbar extension range of motion, LBP visual analogue score, LBP functional disability questionnaires and MRI lumbar FJ detected synovitis and their grading.

resultsBoth groups showed a significant improvement in all mentioned parameters at follow-up after 3 months. However, PRP injections promoted better performance in terms of MRI synovitis grade in all lumbar FJ levels compared to CS injections.

conclusionBoth PRP and CS injections were effective in improving MRI-detected FJ synovitis while concurrently improving all examined parameters at follow-up after 3 months. However, PRP promoted better improvement in MRI-detected synovitis grade, suggesting that it may be a better treatment option for longer duration efficacy.TRN: NCT04860531- 1/3/2021.

Indexed as

Joint DiseasesPlatelet-Rich PlasmaSynovitisZygapophyseal JointAdrenal Cortex HormonesHumansInjections, Intra-ArticularProspective StudiesTreatment OutcomeAdrenal Cortex Hormonescorticosteroidslumbar facet jointplatelet rich plasmasynovitis

Identifiers

PMID36379530
PMCPMC10043910
OpenAlexW4309360693

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read40
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.