ReviewJournal of the American Association for Laboratory Animal Science : JAALAS2022
A Review of Long-acting Parenteral Analgesics for Mice and Rats.
Review in Journal of the American Association for Laboratory Animal Science : JAALAS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Onset of Analgesia in Rats (Rattus norvegicus) for Three Buprenorphine Formulations.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Locomotion-induced neural activity independent of auditory feedback in the mouse inferior colliculus.iScience · 2026Article
- Pharmacokinetics and Analgesic Efficacy of a Novel Extended-Release Buprenorphine Formulation in Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Efficacy and Pharmacokinetics of 3 Sustained-Release Buprenorphine Formulations in Cairo Spiny Mice (Acomys cahirinus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Pharmacokinetics and preliminary data on safety of meloxicam subcutaneous extended-release formulation in Sprague-Dawley rats.Frontiers in veterinary science · 2026Article
- The Analgesic Effect of Two Different Extended-Release Meloxicam Formulations for Attenuation of Hypersensitivity in Rats (Rattus norvegicus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Evaluation of Extended- and Immediate-Release Buprenorphine Formulations on Pharmacokinetics and Injection Site Lesions in Different Strains and Sex of Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Current practices of pain assessment and analgesic use in laboratory mice: A 2022 FELASA Working Group survey.Laboratory animals · 2025Article
- Reporting practices of anesthetic and analgesic use in rodent orthopedic research.Scientific reports · 2024Article
- Pharmacokinetics of Extended-release Buprenorphine and Clinical Efficacy for Postoperative Pain Management in the Domestic Ferret (Journal of the American Association for Laboratory Animal Science : JAALAS · 2024Article
- Refining pain management in mice by comparing multimodal analgesia and NSAID monotherapy for neurosurgical procedures.Scientific reports · 2024Article
- Licofelone, a Dual COX/LOX Inhibitor, Ameliorates Paclitaxel-Induced Mechanical Allodynia in Rats in a Cannabinoid Receptor-Dependent Manner.Biomedicines · 2024Article
- Pharmacokinetic Evaluation of a Topical Extended-release Analgesic in Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2024Article
- Mouse and Rat Anesthesia and Analgesia.Current protocols · 2024Article
- Evaluation and comparison of pharmacokinetic profiles and safety of two extended-release buprenorphine formulations in common marmosets (Callithrix jacchus).Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Appropriate analgesia is a crucial part of rodent postoperative and postprocedural pain. Providing appropriate analgesia is an ethical obligation, a regulatory requirement, and an essential element of obtaining quality scientific results and conducting reproducible data. Meeting these requirements is facilitated by practical, efficient and safe delivery methods for providing analgesia. Over the last decade, long-acting analgesics have gained widespread use in research animal medicine to avoid or treat postoperative or postprocedural pain while minimizing handling-related time and stress. Long-acting formulations of analgesics suitable for rodents are available for opioids, NSAIDs, and local anesthetics. The goal of this review is to summarize the currently available long-acting formulations of analgesics for rodents and to provide recommendations to veterinarians and researchers regarding their use.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.