Evidence map›Paper›PMID 36379270›Full record

ArticleBiochimica et biophysica acta. Bioenergetics2023

Spectroscopic identification of the catalytic intermediates of cytochrome c oxidase in respiring heart mitochondria.

Raul Covian, Lanelle O Edwards, Bertrand M Lucotte, Robert S Balaban

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochimica et biophysica acta. Bioenergetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Early activation of bioenergetic metabolism powers bacterial spore germination.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raul CovianLaboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, United States of America. Electronic address: raul.coviangarcia@nih.gov.
Lanelle O EdwardsLaboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, United States of America.
Bertrand M LucotteLaboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, United States of America.
Robert S BalabanLaboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, United States of America. Electronic address: balabanr@nhlbi.nih.gov.
National Institutes of Health · US

Funding

Control Of Cellular Energy MetabolismZIAHL004601 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI BALABAN, ROBERT · 2009 to 2023
$24.4M
CONTROL OF CELLULAR ENERGY METABOLISMZ01HL004601 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI BALABAN, ROBERT S · 1988 to 2008
$4.4M
Intramural NIH HHS Z01 HL004601Intramural NIH HHS ZIA HL004601
6 · The paper itself

Abstract

The catalytic cycle of cytochrome c oxidase (COX) couples the reduction of oxygen to the translocation of protons across the inner mitochondrial membrane and involves several intermediate states of the heme a

Indexed as

Electron Transport Complex IVMitochondria, HeartCytochromes cHemeOxygenSpectrum AnalysisCytochromes cElectron Transport Complex IVHemeOxygenCytochrome c oxidaseelectron transferMembrane potentialMitochondriaRespirationSpectroscopy

Identifiers

PMID36379270
PMCPMC9998343
OpenAlexW4309047714

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.