Evidence map›Paper›PMID 36379005›Full record

ArticleACS sensors2022

Catalyst-Free Aqueous Hyperpolarized [1-

Andreas B Schmidt, Henri de Maissin, Isaiah Adelabu, Shiraz Nantogma, Jessica Ettedgui, Patrick TomHon, Boyd M Goodson, Thomas Theis, Eduard Y Chekmenev

Abstract read
In one paragraph

Article in ACS sensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. High-resolution microtesla in-situJournal of magnetic resonance (San Diego, Calif. : 1997) · 2026
    Article
  5. Review
  6. Article
  7. Ultra-low fieldCommunications chemistry · 2026
    Article
  8. Multidimensional pH-Temperature Mapping of SABRE-SHEATHThe journal of physical chemistry. B · 2025
    Article
  9. EfficientJournal of magnetic resonance open · 2025
    Article
  10. Scalable Hyperpolarized MRI Enabled by Ace-SABRE of [1-Angewandte Chemie (International ed. in English) · 2025
    Article
  11. High HThe journal of physical chemistry letters · 2025
    Article
  12. Article
  13. Article
  14. Theranostics · 2025
    Article
  15. Article
  16. Article
  17. In vivo Metabolic Sensing of Hyperpolarized [1-Angewandte Chemie (International ed. in English) · 2024
    Article
  18. Article
  19. The journal of physical chemistry letters · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andreas B SchmidtIntegrative Biosciences (Ibio), Department of Chemistry, Karmanos Cancer Institute (KCI), Wayne State University, 5101 Cass Ave, Detroit, Michigan 48202, United States.ORCID 0000-0001-8944-7463
Henri de MaissinGerman Cancer Consortium (DKTK), Partner Site Freiburg, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.
Isaiah AdelabuIntegrative Biosciences (Ibio), Department of Chemistry, Karmanos Cancer Institute (KCI), Wayne State University, 5101 Cass Ave, Detroit, Michigan 48202, United States.
Shiraz NantogmaIntegrative Biosciences (Ibio), Department of Chemistry, Karmanos Cancer Institute (KCI), Wayne State University, 5101 Cass Ave, Detroit, Michigan 48202, United States.
Jessica EttedguiChemistry and Synthesis Center, National Heart, Lung, Blood Institute, 9800 Medical Center Drive, Building B, Room #2034, Rockville, Maryland 20850, United States.
Patrick TomHonDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina 27606, United States.ORCID 0000-0003-3202-9812
Boyd M GoodsonSchool of Chemical & Biomolecular Sciences and Materials Technology Center, Southern Illinois University, Carbondale, Illinois 62901, United States.ORCID 0000-0001-6079-5077
Thomas TheisDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina 27606, United States.ORCID 0000-0001-6779-9978
Eduard Y ChekmenevIntegrative Biosciences (Ibio), Department of Chemistry, Karmanos Cancer Institute (KCI), Wayne State University, 5101 Cass Ave, Detroit, Michigan 48202, United States.ORCID 0000-0002-8745-8801

Funding

Molecular MRI of Brain Metabolism Enabled by Long-Lived Spin StatesR01EB029829 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI THEIS, THOMAS · 2020 to 2020
$807k
500 MHz NMR SpectrometerS10OD028488 · OD · WAYNE STATE UNIVERSITY · PI ALLEN, MATTHEW J · 2021 to 2021
$600k
NIBIB NIH HHS R01 EB029829NIH HHS S10 OD028488
6 · The paper itself

Abstract

Despite great successes in oncology, patient outcomes are often still discouraging, and hence the diagnostic imaging paradigm is increasingly shifting toward functional imaging of the pathology to better understand individual disease biology and to personalize therapies. The dissolution Dynamic Nuclear Polarization (d-DNP) hyperpolarization method has enabled unprecedented real-time MRI sensing of metabolism and tissue pH using hyperpolarized [1-

Indexed as

Magnetic Resonance ImagingPyruvic AcidHumansMagnetic Resonance SpectroscopySolubilityWaterPyruvic AcidWaterBiosensorshyperpolarizationimaging agentsmagnetic resonance imagingNMR spectroscopyParahydrogenPyruvateSABRE

Identifiers

PMID36379005
PMCPMC9983023

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.