Evidence map›Paper›PMID 36378832›Full record

ArticleNeurourology and urodynamics2023

Clinical hypnosis can reduce lower urinary tract symptoms in individuals with chronic pain.

Lindsey C McKernan, Erin L Connors, Anna M Ryden, Michael T M Finn, Ahra Kim, Simon N Vandekar, Roger R Dmochowski, W Stuart Reynolds

Open access · greenAbstract read
In one paragraph

Article in Neurourology and urodynamics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. The Psychosocial Impact of Urinary Dysfunction.Urology research & practice · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lindsey C McKernanDepartment of Psychiatry & Behavioral Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0001-9419-8502
Erin L ConnorsDepartment of Physical Medicine & Rehabilitation, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Anna M RydenDepartment of Physical Medicine & Rehabilitation, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Michael T M FinnHelen DeVos Children's Hospital, Grand Rapids, Michigan, USA.
Ahra KimDepartment of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Simon N VandekarDepartment of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Roger R DmochowskiDepartment of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0002-9838-9178
W Stuart ReynoldsDepartment of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0003-3444-1421
Vanderbilt University · USHelen DeVos Children's Hospital · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Central Sensitization and Psychosocial Impacts on Overactive BladderR01DK128293 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MCKERNAN, LINDSEY COLMAN, SEBESTA, ELISABETH M · 2021 to 2024
$2.0M
Stress and Anxiety Effects on Overactive Bladder: A Controlled StudyR01DK129624 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MCKERNAN, LINDSEY COLMAN, SEBESTA, ELISABETH M · 2021 to 2025
$2.0M
Optimizing Psychosocial Treatment of Interstitial Cystitis/Bladder Pain SyndromeK23DK118118 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MCKERNAN, LINDSEY COLMAN · 2019 to 2022
$810k
NCATS NIH HHS UL1 TR002243NIDDK NIH HHS K23 DK118118NIDDK NIH HHS R01 DK128293NIDDK NIH HHS R01 DK129624NIH HHS
6 · The paper itself

Abstract

study purposeLower urinary tract symptoms (LUTS) can occur in chronic pain populations at high rates and drastically affect quality of life. Hypnosis is a nonpharmacological treatment used in chronic pain known to have beneficial implications to health outside of pain reduction. This study evaluated the potential for hypnosis to reduce LUTS in a sample of individuals with chronic pain, if baseline LUTS severity affected outcomes, and specific LUTS that may respond to hypnosis.

methodsSixty-four adults with chronic pain and LUTS at a level of detectable symptom change (American Urological Association Symptom Index, AUASI   3) participated in an 8-week group hypnosis protocol. Participants completed validated assessments of LUTS, pain, and overall functioning before, after, 3- and 6-months posttreatment. Linear mixed effects models assessed improvement in LUTS over time while accounting for known factors associated with outcome (e.g., age, gender). The interaction of baseline symptom severity and treatment assessed the potential effect of baseline symptoms on change scores.

resultsParticipants experienced significant and meaningful improvements in LUTS following group hypnosis (p = 0.006). There was a significant interaction between baseline symptom severity and treatment (p < 0.001), such that those with severe symptoms experienced the most pronounced gains over time (e.g., an 8.8 point reduction). Gains increased over time for those with moderate and severe symptoms. Changes in LUT symptoms occurred independently of pain relief.

conclusionsThis pilot study suggests hypnosis has the potential to drastically improve LUTS in individuals with chronic pain, even when pain reduction does not occur. Results provide initial evidence for the treatment potential of hypnosis in urologic pain (and possibly non-pain/benign) populations, with randomized trials needed for definitive outcomes.

Indexed as

Chronic PainHypnosisAdultHumansPilot ProjectsQuality of Lifechronic paincomplementary therapieshypnosislower urinary tract symptomspsychotherapy

Identifiers

PMID36378832
PMCPMC10239668
OpenAlexW4309162487

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.