Evidence map›Paper›PMID 36378808›Full record

ArticleEnvironmental science & technology2022

Dietary Intake Contributed the Most to Chlorinated Paraffin Body Burden in a Norwegian Cohort.

Bo Yuan, Line Småstuen Haug, Joo Hui Tay, Juan Antonio Padilla-Sánchez, Eleni Papadopoulou, Cynthia A de Wit

Open access · hybridAbstract read
In one paragraph

Article in Environmental science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bo YuanDepartment of Environmental Science, Stockholm University, StockholmSE-10691, Sweden.ORCID 0000-0002-2043-8128
Line Småstuen HaugDepartment for Food Safety, Norwegian Institute of Public Health, OsloNO-0213, Norway.
Joo Hui TayDepartment of Environmental Science, Stockholm University, StockholmSE-10691, Sweden.
Juan Antonio Padilla-SánchezDepartment for Food Safety, Norwegian Institute of Public Health, OsloNO-0213, Norway.ORCID 0000-0003-0489-1237
Eleni PapadopoulouDepartment for Food Safety, Norwegian Institute of Public Health, OsloNO-0213, Norway.
Cynthia A de WitDepartment of Environmental Science, Stockholm University, StockholmSE-10691, Sweden.ORCID 0000-0001-8497-2699
Norwegian Institute of Public Health · NOStockholm University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Determining the major human exposure pathways is a prerequisite for the development of effective management strategies for environmental pollutants such as chlorinated paraffins (CPs). As a first step, the internal and external exposure to CPs were quantified for a well-defined human cohort. CPs in participants' plasma and diet samples were analyzed in the present study, and previous results on paired air, dust, and hand wipe samples were used for the total exposure assessment. Both one compartment pharmacokinetic modeling and forensic fingerprinting indicate that dietary intake contributed the most to body burden of CPs in this cohort, contributing a median of 60-88% of the total daily intakes. The contribution from dust ingestion and dermal exposure was greater for the intake of long-chain CPs (LCCPs) than short-chain CPs (SCCPs), while the contribution from inhalation was greater for the intake of SCCPs than medium-chain CPs (MCCPs) and LCCPs. Significantly higher concentrations of SCCPs and MCCPs were observed in diets containing butter and eggs, respectively (

Indexed as

Hydrocarbons, ChlorinatedParaffinBody BurdenChinaDustEatingEnvironmental MonitoringHumansDustHydrocarbons, ChlorinatedParaffinchlorinated paraffinscohort studydietary intakeexternal exposure pathwayshuman exposureplasma

Identifiers

PMID36378808
PMCPMC9730849
OpenAlexW4309158938

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.