Evidence map›Paper›PMID 36378482›Full record

ReviewWorld journal of pediatrics : WJP2023

Monkeypox and the perinatal period: what does maternal-fetal medicine need to know?

Kai Yan, Lu-Kun Tang, Fei-Fan Xiao, Peng Zhang, Chun-Mei Lu, Li-Yuan Hu, Lai-Shuan Wang, Guo-Qiang Cheng, Wen-Hao Zhou

Open access · bronzeAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of pediatrics : WJP, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kai YanDepartment of Neonatology, Children Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Lu-Kun TangKunming Medical University, Kunming, 678400, China.
Fei-Fan XiaoDepartment of Neonatology, Children Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Peng ZhangDepartment of Neonatology, Children Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Chun-Mei LuDepartment of Neonatology, Children Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Li-Yuan HuDepartment of Neonatology, Children Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Lai-Shuan WangDepartment of Neonatology, Children Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Guo-Qiang ChengDepartment of Neonatology, Children Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Wen-Hao ZhouDepartment of Neonatology, Children Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China. zhouwenhao@fudan.edu.cn.ORCID 0000-0001-8956-7238
Children's Hospital of Fudan University · CNFudan University · CNKunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter the global elimination of smallpox, monkeypox has become the most threatening orthopoxvirus to human health. Very few studies have been reported on pregnant women and newborns. In the case of monkeypox infection, the virus can cause serious adverse pregnancy events in women, which can lead to fetal or neonatal death. DATA SOURCES: We made a comprehensive review after an extensive literature search in the PubMed/Medline database and websites concerning smallpox and monkeypox.

resultsTwo case reports reported a total of nine pregnant women, six of whom had fetal deaths. In the autopsy of a stillbirth, researchers found that the placenta was infected with monkeypox virus, but the mechanism of infection remains unclear. Smallpox vaccine should be administered to acutely exposed pregnant women and newborns. Several novel recombinant vaccinia immunogloblin (rVIG) and human-specific monoclonal antibodies are being developed for the prevention and treatment of monkeypox virus infection. After the fetus was delivered, the newborn should take a bath as soon as possible to remove the amniotic fluid and dirt from the body. The appropriate isolation protocol for the newborn should be selected according to the infection status of the mother. It is not known whether monkeypox virus is present in breast milk, and pasteurized breast milk can be given to newborns when breastfeeding is considered.

conclusionThis review presents an overview of monkeypox in the perinatal period and guides the future research direction.

Indexed as

Mpox, MonkeypoxSmallpoxSmallpox VaccineFemaleHumansInfant, NewbornPerinatologyPregnancySmallpox VaccineFetalMaternalMonkeypoxNewborn

Identifiers

PMID36378482
PMCPMC9665008
OpenAlexW4309243468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.