Evidence map›Paper›PMID 36378332›Full record

ArticleParasitology research2023

Resistance of Blastocystis to chlorine and hydrogen peroxide.

Rubén Martín-Escolano, Geok Choo Ng, Kevin S W Tan, C Rune Stensvold, Eleni Gentekaki, Anastasios D Tsaousis

Open access · hybridAbstract read
In one paragraph

Article in Parasitology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. ExploringJournal of medical microbiology · 2026
    Review
  2. Review
  3. Article
  4. Identification ofFood and waterborne parasitology · 2024
    Article
  5. Article
  6. Circulation and colonisation ofEpidemiology and infection · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Rubén Martín-EscolanoLaboratory of Molecular and Evolutionary Parasitology, RAPID Group, School of Biosciences, University of Kent, Canterbury, CT2 7NJ, UK.
Geok Choo NgDepartment of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore, 117545, Singapore.
Kevin S W TanDepartment of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore, 117545, Singapore.
C Rune StensvoldDepartment of Bacteria, Parasites and Fungi, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen S, Denmark.
Eleni GentekakiGut Microbiome Research Group, Mae Fah Luang University, Chiang Rai, 57100, Thailand. gentekaki.ele@mfu.ac.th.
Anastasios D TsaousisLaboratory of Molecular and Evolutionary Parasitology, RAPID Group, School of Biosciences, University of Kent, Canterbury, CT2 7NJ, UK. A.Tsaousis@kent.ac.uk.
National University of Singapore · SGUniversity of Kent · GBMae Fah Luang University · THStatens Serum Institut · DK

Funding

Biotechnology and Biological Sciences Research Council BB/M009971/1EU COST Action CA21105Interreg-2-seas H4DC
6 · The paper itself

Abstract

Blastocystis is a ubiquitous, widely distributed protist inhabiting the gastrointestinal tract of humans and other animals. The organism is genetically diverse, and so far, at least 28 subtypes (STs) have been identified with ST1-ST9 being the most common in humans. The pathogenicity of Blastocystis is controversial. Several routes of transmission have been proposed including fecal-oral (e.g., zoonotic, anthroponotic) and waterborne. Research on the latter has gained traction in the last few years with the organism having been identified in various bodies of water, tap water, and rainwater collection containers including water that has been previously filtered and/or chlorinated. Herein, we assessed the resistance of 11 strains maintained in culture, spanning ST1-ST9 to various chlorine and hydrogen peroxide concentrations for 24 h, and performed recovery assays along with re-exposure. Following the treatment with both compounds, all subtypes showed increased resistance, and viability could be visualized at the cellular level. These results are hinting at the presence of mechanism of resistance to both chlorine and hydrogen peroxide. As such, this pilot study can be the platform for developing guidelines for water treatment processes.

Indexed as

BlastocystisBlastocystis InfectionsAnimalsChlorineFecesGenetic VariationHumansHydrogen PeroxidePhylogenyPilot ProjectsPrevalenceChlorineHydrogen PeroxideBlastocystisChlorine resistanceHydrogen peroxideTransmission dynamicsWater

Identifiers

PMID36378332
PMCPMC9816239
OpenAlexW4309094525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.