Evidence map›Paper›PMID 36377882›Full record

ArticlemSphere2022

Genetic Predictive Factors for Nonsusceptible Phenotypes and Multidrug Resistance in Expanded-Spectrum Cephalosporin-Resistant Uropathogenic Escherichia coli from a Multicenter Cohort: Insights into the Phenotypic and Genetic Basis of Coresistance.

Nicole Jackson, Cheyenne R Belmont, Nicole J Tarlton, Yuan Hu Allegretti, Sheila Adams-Sapper, Yolanda Yue Huang, Clarissa A Borges, Bradley W Frazee, Danka Florence-Petrovic, Clarisse Hufana and 17 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Antimicrobial resistance profiles ofJAC-antimicrobial resistance · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 8 institutions in 1 country.

Nicole Jackson *School of Public Health, Division of Infectious Diseases and Vaccinology, University of California, Berkeleygrid.47840.3f, California, USA.ORCID 0000-0002-0202-3658
Cheyenne R Belmont *School of Public Health, Division of Epidemiology, University of California, Berkeleygrid.47840.3f, California, USA.
Nicole J TarltonDepartment of Microbiology, BioAmp Diagnostics, Inc., San Carlos, California, USA.
Yuan Hu AllegrettiSchool of Public Health, Division of Epidemiology, University of California, Berkeleygrid.47840.3f, California, USA.ORCID 0000-0002-3031-9341
Sheila Adams-SapperSchool of Public Health, Division of Infectious Diseases and Vaccinology, University of California, Berkeleygrid.47840.3f, California, USA.
Yolanda Yue HuangDivision of Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Clarissa A BorgesSchool of Public Health, Division of Infectious Diseases and Vaccinology, University of California, Berkeleygrid.47840.3f, California, USA.
Bradley W FrazeeDepartment of Emergency Medicine, Highland Hospitalgrid.414076.0, Alameda Health Systemgrid.413529.8, Oakland, California, USA.
Danka Florence-PetrovicDepartment of Laboratory Medicine and Pathology, Highland Hospitalgrid.414076.0, Alameda Health Systemgrid.413529.8, Oakland, California, USA.
Clarisse HufanaDepartment of Microbiology, BioAmp Diagnostics, Inc., San Carlos, California, USA.
Anna ParkerSchool of Public Health, Division of Infectious Diseases and Vaccinology, University of California, Berkeleygrid.47840.3f, California, USA.
Claire F MastrangeloSchool of Public Health, Division of Infectious Diseases and Vaccinology, University of California, Berkeleygrid.47840.3f, California, USA.
Shevya AwasthiSchool of Public Health, Division of Infectious Diseases and Vaccinology, University of California, Berkeleygrid.47840.3f, California, USA.
Isha KaneDepartment of Microbiology, BioAmp Diagnostics, Inc., San Carlos, California, USA.
Zlatan CoralicDepartment of Pharmacy, University of California, San Franciscogrid.266102.1, California, USA.
Steve MillerDepartment of Laboratory Medicine, University of California, San Franciscogrid.266102.1, California, USA.ORCID 0000-0002-9188-3392
Joycelyn DiazDepartment of Laboratory Medicine, University of California, San Franciscogrid.266102.1, California, USA.
Christopher FeeDepartment of Laboratory Medicine, University of California, San Franciscogrid.266102.1, California, USA.
Cassiana E BittencourtDepartment of Pathology and Laboratory Medicine, University of California, Irvinegrid.266093.8, California, USA.
Omai GarnerDepartment of Pathology and Laboratory Medicine, University of California, Los Angelesgrid.19006.3e, California, USA.ORCID 0000-0002-7366-2692
Sukantha ChandrasekaranDepartment of Pathology and Laboratory Medicine, University of California, Los Angelesgrid.19006.3e, California, USA.ORCID 0000-0002-6232-5535
Claudia CrandallJohn Muir Microbiology, John Muir Healthgrid.414728.c, Concord, California, USA.
Julian C MarchaJohn Muir Microbiology, John Muir Healthgrid.414728.c, Concord, California, USA.
Mir H NoorbakhshSutter Shared Lab, Sutter Health, Livermore, California, USA.
Patricia Rodrigues-WongSutter Shared Lab, Sutter Health, Livermore, California, USA.
Tara R deBoerDepartment of Chemistry, BioAmp Diagnostics, Inc., San Carlos, California, USA.
Lee W RileySchool of Public Health, Division of Infectious Diseases and Vaccinology, University of California, Berkeleygrid.47840.3f, California, USA.
University of California, Berkeley · USUniversity of California, San Francisco · USAlameda Health System · USJohn Muir Health · USSutter Health · USUniversity of California, Los Angeles · USLawrence Berkeley National Laboratory · USUniversity of California, Irvine · US

Funding

Consortium for drug-resistant Gram-negative pathogen detectionR01AI117064 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI LEE, LUKE P., MURTHY, NIREN · 2015 to 2019
$5.7M
NIAID NIH HHS R01 AI117064
6 · The paper itself

Abstract

Antimicrobial resistance in urinary tract infections (UTIs) is a major public health concern. This study aims to characterize the phenotypic and genetic basis of multidrug resistance (MDR) among expanded-spectrum cephalosporin-resistant (ESCR) uropathogenic Escherichia coli (UPEC) causing UTIs in California patient populations. Between February and October 2019, 577 ESCR UPEC isolates were collected from patients at 6 clinical laboratory sites across California. Lineage and antibiotic resistance genes were determined by analysis of whole-genome sequence data. The lineages ST131, ST1193, ST648, and ST69 were predominant, representing 46%, 5.5%, 4.5%, and 4.5% of the collection, respectively. Overall, 527 (91%) isolates had an expanded-spectrum β-lactamase (ESBL) phenotype, with

Indexed as

Escherichia coli InfectionsUropathogenic Escherichia colibeta-LactamasesCephalosporinsDrug Resistance, Multiple, BacterialHumansMonobactamsPhenotypebeta-LactamasesCephalosporinsMonobactamsESBLexpanded-spectrum cephalosporin resistancemultilocus sequence typeuropathogenic E. coliwhole-genome sequence

Identifiers

PMID36377882
PMCPMC9769571
OpenAlexW4309048217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.