Evidence map›Paper›PMID 36377866›Full record

ArticlemBio2022

UBXN3B Controls Immunopathogenesis of Arthritogenic Alphaviruses by Maintaining Hematopoietic Homeostasis.

Tingting Geng, Duomeng Yang, Tao Lin, Jason G Cahoon, Penghua Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tingting GengDepartment of Immunology, School of Medicine, the University of Connecticut Health Center, Farmington, Connecticut, USA.
Duomeng YangDepartment of Immunology, School of Medicine, the University of Connecticut Health Center, Farmington, Connecticut, USA.
Tao LinDepartment of Immunology, School of Medicine, the University of Connecticut Health Center, Farmington, Connecticut, USA.
Jason G CahoonDepartment of Immunology, School of Medicine, the University of Connecticut Health Center, Farmington, Connecticut, USA.
Penghua WangDepartment of Immunology, School of Medicine, the University of Connecticut Health Center, Farmington, Connecticut, USA.ORCID 0000-0002-7332-1871
UConn Health · US

Funding

The role of NLRP6 and DHX15 in control of infection by RNA virusesR01AI127865 · NIAID · YALE UNIVERSITY · PI FIKRIG, EROL, FLAVELL, RICHARD A · 2018 to 2022
$2.1M
The role of UBXNs in antiviral immunityR01AI132526 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI WANG, PENGHUA · 2018 to 2022
$2.1M
A critical role for UBXN3B in IgG homeostasis and maternal transferR21AI155820 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI WANG, PENGHUA · 2021 to 2022
$451k
NIAID NIH HHS R01 AI127865NIAID NIH HHS R01 AI132526NIAID NIH HHS R21 AI155820
6 · The paper itself

Abstract

Ubiquitin regulatory X domain-containing proteins (UBXN) might be involved in diverse cellular processes. However, their

Indexed as

Chikungunya FeverChikungunya virusVirusesAnimalsAntiviral AgentsHumansMiceUbiquitinsVirus ReplicationAntiviral AgentsUbiquitinsalphavirusarthritogenicChikungunya virushematopoiesisUBXN

Identifiers

PMID36377866
PMCPMC9765034
OpenAlexW4309095894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.