Evidence map›Paper›PMID 36377330›Full record

SynthesisKorean journal of anesthesiology2023

Role of carotid corrected flow time and peak velocity variation in predicting fluid responsiveness: a systematic review and meta-analysis.

Deepak Singla, Bhavna Gupta, Pragya Varshney, Mishu Mangla, Beeraling Ningappa Walikar, Tiajem Jamir

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Korean journal of anesthesiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07245485 (Fluid Responsiveness in Coronary Artery Bypass Surgery), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07245485 completednot on this mapstarted 2025, after this paper: background citation

Fluid Responsiveness in Coronary Artery Bypass Surgery: The Role of Carotid Artery Ultrasound and Passive Leg Raising Maneuver

TypeobservationalSponsorAnkara City Hospital BilkentRan2025 to 2026Enrolled50ConditionsFluid Responsiveness, Passive Leg Raising, Corrected Carotid Flow Time
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Deepak SinglaDepartment of Anesthesiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Bhavna GuptaDepartment of Anesthesiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Pragya VarshneyDepartment of Anesthesiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Mishu ManglaDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, Hyderabad, Telangana, India.
Beeraling Ningappa WalikarDepartment of Anesthesiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Tiajem JamirDepartment of Anesthesiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDynamic parameters used for predicting fluid responsiveness require special equipment and are minimally invasive. Therefore, recent interest in the use of carotid artery ultrasound parameters, such as carotid corrected flow time (FTc) and peak velocity variation (ΔVpeak) has grown. Therefore, we performed this systematic review and meta-analysis to assess the ability of carotid FTc and/or ΔVpeak to accurately predict fluid responsiveness.

methodsWe searched the PubMed and Embase databases for articles evaluating the diagnostic accuracy of carotid FTc or ΔVpeak for predicting fluid responsiveness. Two independent authors performed the search and selected studies published until May 2022. The studies were assessed for the inclusion and exclusion criteria using Rayyan (Rayyan Systems Inc., 2022).

resultsTen studies (n=438) that fulfilled the inclusion criteria were selected. Studies were divided into those assessing carotid FTc and those assessing carotid ΔVpeak. Five studies (six datasets) assessed FTc. The pooled sensitivity and specificity of carotid FTc were 0.76 and 0.88, respectively. The summary receiver operating characteristic (SROC) curve for carotid FTc had an area under the curve (AUC) of 0.9092, with a Q value of 0.8412. Seven studies calculated carotid ΔVpeak. The pooled sensitivity and specificity for ΔVpeak were 0.83 and 0.81, respectively. The SROC curve had an AUC of 0.8941 and a Q value of 0.8250.

conclusionsOur meta-analysis showed that both carotid FTc and ΔVpeak are useful for predicting fluid responsiveness in anesthesia and critical care settings with good specificity and sensitivity.

Indexed as

Carotid ArteriesRespiration, ArtificialBlood Flow VelocityHumansROC CurveSensitivity and SpecificityCardiac outputCarotid arteriesEchocardiographyFluid therapyHemodynamic monitoringUltrasonography.

Identifiers

PMID36377330
PMCPMC10244609

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.