Evidence map›Paper›PMID 36377296›Full record

ArticleSurgical innovation2023

Interobserver Variability in the Assessment of Fluorescence Angiography in the Colon.

Antonio S Soares, Neil T Clancy, Sophia Bano, Imran Raza, Michelle Diana, Laurence B Lovat, Danail Stoyanov, Manish Chand

Open access · hybridAbstract read
In one paragraph

Article in Surgical innovation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. AUGUR-AIM: Clinical validation of an artificial intelligence indocyanine green fluorescence angiography expert representer.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Antonio S Soares4919Wellcome EPSRC Centre for Interventional and Surgical Sciences (WEISS), London, UK.ORCID 0000-0001-7773-2427
Neil T Clancy4919Wellcome EPSRC Centre for Interventional and Surgical Sciences (WEISS), London, UK.
Sophia Bano4919Wellcome EPSRC Centre for Interventional and Surgical Sciences (WEISS), London, UK.
Imran RazaUniversity College London Hospital, 8964University College London Hospitals NHS Trust, London, UK.
Michelle DianaIRCAD, Research Institute Against Digestive Cancer, Strasbourg, France.ORCID 0000-0002-1390-8486
Laurence B Lovat4919Wellcome EPSRC Centre for Interventional and Surgical Sciences (WEISS), London, UK.
Danail Stoyanov4919Wellcome EPSRC Centre for Interventional and Surgical Sciences (WEISS), London, UK.
Manish Chand4919Wellcome EPSRC Centre for Interventional and Surgical Sciences (WEISS), London, UK.
Wellcome / EPSRC Centre for Interventional and Surgical Sciences · GBLaboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie · FRUniversity College London Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFluorescence angiography in colorectal surgery is a technique that may lead to lower anastomotic leak rates. However, the interpretation of the fluorescent signal is not standardised and there is a paucity of data regarding interobserver agreement. The aim of this study is to assess interobserver variability in selection of the transection point during fluorescence angiography before anastomosis.

methodsAn online survey with still images of fluorescence angiography was distributed through colorectal surgery channels containing images from 13 patients where several areas for transection were displayed to be chosen by raters. Agreement was assessed overall and between pre-planned rater cohorts (experts vs non-experts; trainees vs consultants; colorectal specialists vs non colorectal specialists), using Fleiss' kappa statistic.

results101 raters had complete image ratings. No significant difference was found between raters when choosing a point of optimal bowel transection based on fluorescence angiography still images. There was no difference between pre-planned cohorts analysed (experts vs non-experts; trainees vs consultants; colorectal specialists vs non colorectal specialists). Agreement between these cohorts was poor (<.26).

conclusionWhilst there is no learning curve for the technical adoption of FA, understanding the fluorescent signal characteristics is key to successful use. We found significant variation exists in interpretation of static fluorescence angiography data. Further efforts should be employed to standardise fluorescence angiography assessment.

Indexed as

Colorectal NeoplasmsAnastomosis, SurgicalAnastomotic LeakColoring AgentsFluorescein AngiographyHumansIndocyanine GreenObserver VariationColoring AgentsIndocyanine Greencolorectal surgeryergonomics and/or human factors studyimage guided surgery

Identifiers

PMID36377296
PMCPMC12174605
OpenAlexW4309093699

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.