Evidence map›Paper›PMID 36377066›Full record

ArticleJournal of dental research2023

Bone Sialoprotein Is Critical for Alveolar Bone Healing in Mice.

M B Chavez, M H Tan, T N Kolli, C Zachariadou, F Farah, F F Mohamed, E Y Chu, B L Foster

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  14. Functions of secretory calcium-binding phosphoproteins in dental mineralization.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The role of bone sialoprotein in bone healing.Journal of structural biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

M B ChavezDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
M H TanDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
T N KolliDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
C ZachariadouDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
F FarahDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
F F MohamedDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
E Y ChuDivision of Operative Dentistry, Department of General Dentistry, School of Dentistry, University of Maryland, Baltimore, MD, USA.
B L FosterDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.ORCID 0000-0003-3444-0576
The Ohio State University · USUniversity of Iowa · USUniversity of Maryland, Baltimore · US

Funding

Comprehensive Training in Oral &Craniofacial SciencesT32DE014320 · NIDCR · OHIO STATE UNIVERSITY · PI SHERIDAN, JOHN F · 2001 to 2022
$10.2M
Functions of extracellular matrix proteins in dental and skeletal mineralizationR01DE027639 · NIDCR · OHIO STATE UNIVERSITY · PI Brian Lee Foster · 2019 to 2026
$2.3M
Functional domains of bone sialoprotein in dentoalveolar development and healingF30DE030358 · NIDCR · OHIO STATE UNIVERSITY · PI CHAVEZ, MICHAEL B. · 2021 to 2024
$198k
NIDCR NIH HHS F30 DE030358NIDCR NIH HHS R01 DE027639NIDCR NIH HHS T32 DE014320
6 · The paper itself

Abstract

Bone sialoprotein (BSP) is an extracellular matrix (ECM) protein associated with mineralized tissues, particularly bone and cementum. BSP includes functional domains implicated in collagen binding, hydroxyapatite nucleation, and cell signaling, although its function(s) in osteoblast and osteoclast differentiation and function remain incompletely understood. Genetic ablation of BSP in

Indexed as

Dental CementumOsteopontinAnimalsIntegrin-Binding SialoproteinMiceRNA, MessengerSialoglycoproteinsX-Ray MicrotomographyIntegrin-Binding SialoproteinOsteopontinRNA, MessengerSialoglycoproteinsbone biologybone remodeling/regenerationextracellular matrix (ECM)mineralized tissue/developmentosteoblast(s)

Identifiers

PMID36377066
PMCPMC9893390
OpenAlexW4309098091

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.