Evidence map›Paper›PMID 36377055›Full record

ArticlePhysiological reports2022

Ang II acutely stimulates Na,K-pump in cells from proximal tubules by increasing its phosphorylation at S938 via a PI3K/AKT pathway.

Fadia S Hanna, Samaa Alkhouri, Carthic Rajagopalan, Kyungmin Ji, Raymond R Mattingly, Douglas R Yingst

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Plants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fadia S HannaDepartment of Physiology, Wayne State University, School of Medicine, Detroit, Michigan, USA.
Samaa AlkhouriDepartment of Physiology, Wayne State University, School of Medicine, Detroit, Michigan, USA.
Carthic RajagopalanDepartment of Physiology, Wayne State University, School of Medicine, Detroit, Michigan, USA.
Kyungmin JiDepartment of Pharmacology, Wayne State University, School of Medicine, Detroit, Michigan, USA.
Raymond R Mattingly
Douglas R YingstDepartment of Physiology, Wayne State University, School of Medicine, Detroit, Michigan, USA.ORCID 0000-0001-6449-9793
Wayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
Regulation of Ras through the Ras GRF exchange factorR01CA081150 · NCI · WAYNE STATE UNIVERSITY · PI MATTINGLY, RAYMOND R · 2001 to 2005
$1.0M
Mechanisms of Renal Na+ Pump Stimulation by AngiotensinR01DK060752 · NIDDK · WAYNE STATE UNIVERSITY · PI YINGST, DOUGLAS R · 2002 to 2005
$918k
NCI NIH HHS P30 CA022453NCI NIH HHS R01 CA081150NIDDK NIH HHS R01 DK060752
6 · The paper itself

Abstract

Angiotensin II (Ang II)-dependent stimulation of the AT

Indexed as

Angiotensin IIPhosphatidylinositol 3-KinasesAnimalsHumansKidney Tubules, ProximalOpossumsPhosphorylationProto-Oncogene Proteins c-aktRatsSerineSodiumSodium-Potassium-Exchanging ATPaseWortmanninAngiotensin IIPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSerineSodiumSodium-Potassium-Exchanging ATPaseWortmanninangiotensin IINa,K-pumpphosphorylationproximal tubulesignaling

Identifiers

PMID36377055
PMCPMC9663852
OpenAlexW4309115039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.