Evidence map›Paper›PMID 36376863›Full record

ArticleBMC neurology2022

Autoimmune encephalitis after BBIBP-CorV (Sinopharm) COVID-19 vaccination: a case report.

Miguel A Vences, Mary M Araujo-Chumacero, Edu Cardenas, Diego Canales, Arturo Alvarez, Ebelin Barja, Maria Fe Albujar, Diego Urrunaga-Pastor

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Post-COVID-19 Vaccination CNS Magnetic Resonance Imaging Findings: A Systematic Review.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Miguel A VencesDepartamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Avenida Edgardo Rebagliati 490, Jesús María, 15072, Lima, Peru. vens1793@hotmail.com.
Mary M Araujo-ChumaceroDepartamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Avenida Edgardo Rebagliati 490, Jesús María, 15072, Lima, Peru.
Edu CardenasDepartamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Avenida Edgardo Rebagliati 490, Jesús María, 15072, Lima, Peru.
Diego CanalesDepartamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Avenida Edgardo Rebagliati 490, Jesús María, 15072, Lima, Peru.
Arturo AlvarezDepartamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Avenida Edgardo Rebagliati 490, Jesús María, 15072, Lima, Peru.
Ebelin BarjaDepartamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Avenida Edgardo Rebagliati 490, Jesús María, 15072, Lima, Peru.
Maria Fe AlbujarDepartamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Avenida Edgardo Rebagliati 490, Jesús María, 15072, Lima, Peru.
Diego Urrunaga-PastorVicerrectorado de Investigación. Universidad San Ignacio de Loyola, Unidad para la Generación y Síntesis de Evidencias en Salud, Campus 2, avenida La Fontana 750, La Molina, Lima, Peru. diego.urrunaga.pastor1@gmail.com.ORCID http://orcid.org/0000-0002-8339-162X
Hospital Nacional Cayetano Heredia · PEUniversidad San Ignacio de Loyola · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVaccination is an important public health strategy; however, many neurological adverse effects are associated with COVID-19 vaccination, being encephalitis a rare manifestation. CASE PRESENTATION: We present the case of a 33-year-old woman who received the first dose of the BBIBP-CorV vaccine against COVID-19 on April 4 and the second dose on April 28, 2021. Three days after receiving the second dose, she experienced a subacute episode of headache, fever, insomnia, and transient episodes of environment disconnection. We obtained negative results for infectious, systemic, and oncological causes. Brain magnetic resonance imaging showed lesions in the bilateral caudate nucleus and nonspecific demyelinating lesions at the supratentorial and infratentorial compartments. The results of the neuronal autoantibodies panel were negative. She had an adequate response to immunoglobulin and methylprednisolone; however, she experienced an early clinical relapse and received a new cycle of immunosuppressive treatment followed by a satisfactory clinical evolution.

conclusionsWe report the first case of severe encephalitis associated with BBIBP-CorV (Sinopharm) vaccination in Latin America. The patient had atypical imaging patterns, with early clinical relapse and a favorable response to corticosteroid therapy.

Indexed as

COVID-19COVID-19 VaccinesEncephalitisAdultFemaleHashimoto DiseaseHumansRecurrenceVaccinationCOVID-19 VaccinesCOVID-19Drug-related side effects and adverse reactions (source: MeSH NLM)EncephalitisVaccination

Identifiers

PMID36376863
PMCPMC9662115
OpenAlexW4308966164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.