Evidence map›Paper›PMID 36376852›Full record

Trial reportBMC anesthesiology2022

Supraglottic jet oxygenation and ventilation decreased hypoxemia during gastrointestinal endoscopy under deep sedation at high altitudes: a randomized clinical trial.

Bailin Jiang, Yi Li, Deji Ciren, Ouzhu Dawa, Yi Feng, Ciren Laba

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05304923 (Supraglottic Jet Oxygenation and Ventilation), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05304923 naunknown statusnot on this map

Supraglottic Jet Oxygenation and Ventilation (SJOV) for Hypoxemia During Deep Sedation for Gastrointestinal Endoscopy at High-altitude

TypeinterventionalSponsorPeking University People's HospitalRan2022 to 2022Enrolled72ConditionsHypoxia, High AltitudeArmsSupraglottic jet oxygenation and ventilation, Nasal cannula oxygen supply
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Bailin JiangDepartment of Anesthesiology, Tibet Autonomous Region People's Hospital, No.18 Linkuo North Road, Lhasa, Tibet, China.
Yi LiDepartment of Anesthesiology, Tibet Autonomous Region People's Hospital, No.18 Linkuo North Road, Lhasa, Tibet, China.
Deji CirenDepartment of Anesthesiology, Tibet Autonomous Region People's Hospital, No.18 Linkuo North Road, Lhasa, Tibet, China.
Ouzhu DawaDepartment of Anesthesiology, Tibet Autonomous Region People's Hospital, No.18 Linkuo North Road, Lhasa, Tibet, China.
Yi FengDepartment of Anesthesiology, Peking University People's Hospital, No.11 Xizhimen South Street, Xicheng District, Beijing, China. doctor_yifeng@sina.com.
Ciren LabaDepartment of Anesthesiology, Tibet Autonomous Region People's Hospital, No.18 Linkuo North Road, Lhasa, Tibet, China. dr_labaciren@sina.com.
Tibet Autonomous Region People's Hospital · CNPeking University · CNPeking University People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypobaric hypoxia is common at high altitudes. Whether this exacerbates hypoxia during procedural sedation and whether hypoxia can be alleviated by the use of supraglottic jet oxygenation and ventilation (SJOV) are unknown. This study aimed to compare the incidence of hypoxia during gastrointestinal endoscopy under deep sedation at high altitudes with oxygen supply techniques using either a nasal cannula or SJOV.

methodsThis study was conducted from April 2022 to July 2022 in a tertiary hospital located 3650 m above sea level. Adult patients scheduled for routine gastrointestinal endoscopy under sedation were enrolled and randomized 1:1 to receive SJOV or a nasal cannula during sedation. Moderate hypoxia was the primary outcome, defined as an SPO

resultsNone of the patients were lost to follow-up. A total of 72 patients were included in the analysis (36 patients in each group). There were 20 (27.8%) patients who experienced moderate hypoxia events. Significantly fewer hypoxic events occurred in the SJOV group than in the nasal cannula group [3 (8.3%) vs. 17 (47.2%), absolute risk difference (95% CI): - 38.9 (- 57.5, - 20.2) %, risk ratio (RR, 95% CI): 0.18 (0.06, 0.55), P < 0.001]. Significantly fewer patients in the SJOV group experienced mild hypoxia (P < 0.001) and severe hypoxia (P = 0.002). No serious adverse events occurred in either of the groups. The Tibetan ethnic group (P = 0.086) and erythrocytosis (P = 0.287) were not associated with the occurrence of hypoxia events.

conclusionsThe incidence of hypoxia was lower with SJOV than with nasal cannula in patients undergoing gastrointestinal endoscopy under deep sedation at high altitudes. The Tibetan ethnic group and erythrocytosis did not influence the occurrence of hypoxia.

trial registrationThis study was registered at ClinicalTrials.gov (NCT05304923) before enrollment by Dr. Yi Feng on 31/03/2022.

Indexed as

Deep SedationPolycythemiaAdultAltitudeEndoscopy, GastrointestinalHumansHypoxiaOxygenOxygen Inhalation TherapyOxygenAirway managementGastrointestinal endoscopyHigh altitudesHypoxiaSedationSupraglottic jet oxygenation and ventilation (SJOV)Wei nasal jet tube (WNJ)

Identifiers

PMID36376852
PMCPMC9661813
OpenAlexW4308974759

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.