Evidence map›Paper›PMID 36376825›Full record

ArticleBMC immunology2022

Regulatory and effector T cell subsets in tumor-draining lymph nodes of patients with squamous cell carcinoma of head and neck.

Marzieh Norouzian, Fereshteh Mehdipour, Mohammad Javad Ashraf, Bijan Khademi, Abbas Ghaderi

Abstract read
In one paragraph

Article in BMC immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  7. Type I conventional dendritic cells and CD8Frontiers in immunology · 2024
    Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marzieh NorouzianDepartment of Laboratory Sciences, School of Allied Medical Sciences, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Fereshteh MehdipourShiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, P.O. Box: 71345-3119, Shiraz, Iran. mehdipourf@sums.ac.ir.
Mohammad Javad AshrafDepartment of Oral Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Bijan KhademiDepartment of Otolaryngology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Abbas GhaderiShiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, P.O. Box: 71345-3119, Shiraz, Iran. ghaderia@sums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA crucial role for the immune system has been proposed in the establishment and progression of head and neck squamous cell carcinoma (HNSCC). In this study, we investigated the cytokine and regulatory profiles of T cells in tumor draining lymph nodes (TDLNs) of patients with HNSCC.

resultsThe frequencies of CD4

conclusionThis study shed more lights on the changes in immune profile of T cells in TDLNs of HNSCC. Larger tumor size and/or LN involvement were associated with lower frequencies of CD4

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsCD8-Positive T-LymphocytesForkhead Transcription FactorsHumansInterleukin-4Lymph NodesSquamous Cell Carcinoma of Head and NeckT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsTumor Necrosis Factor-alphaForkhead Transcription FactorsInterleukin-4Tumor Necrosis Factor-alphaCytokine profileHead and neck squamous cell carcinomaImmune profileRegulatory T cellsT lymphocytesTumor draining lymph nodes

Identifiers

PMID36376825
PMCPMC9664675

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.