Evidence map›Paper›PMID 36376723›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2023

Using an Endoluminal Functional Lumen Imaging Probe (EndoFLIP™) to Compare Pyloric Function in Patients with Gastroparesis to Patients After Esophagectomy.

Florian Lorenz, Stefanie Brunner, Felix Berlth, Thomas Dratsch, Benjamin Babic, Hans Friedrich Fuchs, Thomas Schmidt, Erkan Celik, Daniel Pinto Dos Santos, Peter Grimminger and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Florian LorenzDepartment of Gastroenterology and Hepatology, Interdisciplinary Endoscopy Unit, University Hospital of Cologne, Cologne, Germany.ORCID 0000-0002-8535-5243
Stefanie BrunnerDepartment of General, Visceral, Cancer and Transplant Surgery, University Hospital of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Felix BerlthDepartment of General, Visceral and Transplantation Surgery, University Hospital of Mainz, Mainz, Germany.
Thomas DratschDepartment of Diagnostic and Interventional Radiology, University Hospital of Cologne, Cologne, Germany.
Benjamin BabicDepartment of General, Visceral, Cancer and Transplant Surgery, University Hospital of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Hans Friedrich FuchsDepartment of General, Visceral, Cancer and Transplant Surgery, University Hospital of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Thomas SchmidtDepartment of General, Visceral, Cancer and Transplant Surgery, University Hospital of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Erkan CelikDepartment of Diagnostic and Interventional Radiology, University Hospital of Cologne, Cologne, Germany.
Daniel Pinto Dos SantosDepartment of Diagnostic and Interventional Radiology, University Hospital of Cologne, Cologne, Germany.
Peter GrimmingerDepartment of General, Visceral and Transplantation Surgery, University Hospital of Mainz, Mainz, Germany.
Christiane Josephine BrunsDepartment of General, Visceral, Cancer and Transplant Surgery, University Hospital of Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Tobias GoeserDepartment of Gastroenterology and Hepatology, Interdisciplinary Endoscopy Unit, University Hospital of Cologne, Cologne, Germany.
Seung-Hun ChonDepartment of Gastroenterology and Hepatology, Interdisciplinary Endoscopy Unit, University Hospital of Cologne, Cologne, Germany. Seung-Hun.Chon@uk-koeln.de.ORCID 0000-0002-8923-6428
University Hospital Cologne · DEJohannes Gutenberg University Mainz · DEGoethe University Frankfurt · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastroparesis (GP) occurs in patients after upper gastrointestinal surgery, in patients with diabetes or systemic sclerosis and in idiopathic GP patients. As pyloric dysfunction is considered one of the underlying mechanisms, measuring this mechanism with EndoFLIP™ can lead to a better understanding of the disease.

methodsBetween November 2021 and March 2022, we performed a retrospective single-centre study of all patients who had non-surgical GP, post-surgical GP and no sign of GP after esophagectomy and who underwent our post-surgery follow-up program with surveillance endoscopies and further exams. EndoFLIP™ was used to perform measurements of the pylorus, and distensibility was measured at 40 ml, 45 ml and 50 ml balloon filling.

resultsWe included 66 patients, and successful application of the EndoFLIP™ was achieved in all interventions (n = 66, 100%). We identified 18 patients suffering from non-surgical GP, 23 patients suffering from GP after surgery and 25 patients without GP after esophagectomy. At 40, 45 and 50 ml balloon filling, the mean distensibility in gastroparetic patients was 8.2, 6.2 and 4.5 mm

conclusionMeasurement with EndoFLIP™ showed that asymptomatic post-surgery patients seem to have a higher pyloric distensibility. Pyloric distensibility and symptoms of GP seem to correspond.

Indexed as

GastroparesisEsophagectomyGastric EmptyingHumansPylorusRetrospective StudiesDelayed gastric conduit emptyingEndoFLIP™EsophagectomyGastroparesisPyloric distensibility

Identifiers

PMID36376723
PMCPMC10073042
OpenAlexW4308945341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.