Evidence map›Paper›PMID 36376635›Full record

SynthesisJournal of general internal medicine2023

Effects of Health Information Exchanges in the Adult Inpatient Setting: a Systematic Review.

Sarah Dupont, John Nemeth, Sara Turbow

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Journal of general internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Electronic connectivity between hospital pairs: impact on emergency department-related utilization.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
  7. Article
  8. Article
  9. Electronic connectivity between hospital pairs: impact on emergency department-related utilization.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sarah DupontDepartment of Family and Preventive Medicine, Emory University School of Medicine, Atlanta, GA, USA. sdupont@emory.edu.ORCID 0000-0001-8282-8984
John NemethWoodruff Health Sciences Center Library, Emory University, Atlanta, GA, USA.
Sara TurbowDepartment of Family and Preventive Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
HRSA HHS D33HP31669NCATS NIH HHS UL1 TR002378NIH HHS UL1-TR002378
6 · The paper itself

Abstract

backgroundHealth information exchanges (HIEs) have proliferated over the last decade, but a gap remains in our understanding of their benefits to patients and the healthcare system. In this systematic review, we provide an updated report on what is known regarding the impacts of HIE on clinical, health care utilization, and cost outcomes in the adult inpatient setting.

methodsWe searched Pubmed, Web of Science, Embase, Cochrane, and Ebsco databases for citations published between January 2015 and August 2021. Eligible studies were English-language experimental or observational studies. We assessed risk of bias via the National Heart Lung and Blood Institute's Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies.

resultsWe identified 11 eligible studies-1 quasi-experimental and 10 observational. Five studies examined readmission rates and 3 found benefits from HIE. Three studies examined mortality with 2 finding benefits from the availability of HIE. Eight studies examined utilization and cost outcomes with 2 finding benefits from HIE, 1 finding poorer outcomes with HIE, and the others finding no impact.

conclusionsEvidence for the impacts of HIE remains largely observational with little direct measure of HIE use during clinical care, making causality difficult to assess. The highly variable outcomes examined by these studies limit meaningful synthesis. The strength of evidence is low that HIE reduces unplanned readmissions and mortality and there is insufficient evidence for the impact of HIE on cost or utilization. The increased number of studies specific to inpatient settings that examine objective outcomes with more rigorous statistical methods is a promising development since prior reviews.

trial registrationPROSPERO 2021 CRD42021274049 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021274049 AMENDMENTS TO PROTOCOL: Initially planned use of the Newcastle-Ottawa quality assessment scale was substituted for the National Heart Lung and Blood Institute's Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies as it was better suited to evaluate the primarily retrospective observational cohort studies identified in the review.

Indexed as

Health Information ExchangeAdultCross-Sectional StudiesHumansInpatientsPatient Acceptance of Health CareRetrospective Studies

Identifiers

PMID36376635
PMCPMC10039134
OpenAlexW4308990232

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.