ArticleJournal of general internal medicine2023
Electronic Advisories Increase Naloxone Prescribing Across Health Care Settings.
Article in Journal of general internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Learning from Misses: Evaluating a Clinical Decision Support for Chronic Pain Management in Primary Care.Applied clinical informatics · 2025Trial
- Health Information Technology Infrastructure and Availability of Medications for Opioid Use Disorder and Naloxone in U.S. Substance Use Disorder Treatment Facilities.The journal of behavioral health services & research · 2026Article
- A Naloxone Best Practice Advisory That Failed to Signal: A Real‑World Evaluation of an Emergency Department.Cureus · 2026Article
- Implementation of an Electronic Health Record Alert to Improve Naloxone Coprescribing for Adult Patients With Cancer at Risk for Opioid Overdose.Journal of the advanced practitioner in oncology · 2025Article
- Naloxone Prescribing Among Long-Term Opioid-Prescribed Patients: Disparities and Opportunities.Cureus · 2025Article
- Academic Detailing to Enhance Adoption of Clinical Decision Support for Patients at Risk of Opioid Overdose.Applied clinical informatics · 2025Article
- Barriers, facilitators, and recommendations to increase the use of a clinical decision support tool for managing chronic pain in primary care.International journal of medical informatics · 2024Article
- Pharmacy Naloxone Standing Order and Community Opioid Fatality Rates Over Time.JAMA network open · 2024Article
- Opioid Prescribing for Chronic Musculoskeletal Conditions: Trends over Time and Implementation of Safe Opioid-Prescribing Practices.Applied clinical informatics · 2023Article
- Glucagon prescribing and prevention of hospitalization for hypoglycemia in a large health system.Diabetes research and clinical practice · 2023Article
- National Trends in Glucagon Prescriptions Among U.S. Adults With Diabetes and End-Stage Kidney Disease Treated by Dialysis: 2013-2017.Diabetes care · 2023Article
- The effectiveness of a noninterruptive alert to increase prescription of take-home naloxone in emergency departments.Journal of the American Medical Informatics Association : JAMIA · 2023Observational
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNaloxone is a life-saving, yet underprescribed, medication that is recommended to be provided to patients at high risk of opioid overdose.
objectiveWe set out to evaluate the changes in prescriber practices due to the use of an electronic health record (EHR) advisory that prompted opioid prescribers to co-prescribe naloxone when prescribing a high-dose opioid. It also provided prescribers with guidance on decreasing opioid doses for safety.
designThis was a retrospective chart abstraction study looking at all opioid prescriptions and all naloxone prescriptions written as emergency department (ED) discharge, inpatient hospital discharge, or outpatient medications, between July 1, 2018, and February 1, 2020. The EHR advisory went live on June 1, 2019. SUBJECTS: Included in the analysis were all adult patients seen in the abovementioned settings at a large county hospital and associated outpatient clinics. MAIN MEASURES: We performed an interrupted time series analysis looking at naloxone prescriptions and daily opioid dosing in morphine milligram equivalents (MMEs), before and after initiation of the EHR advisory. KEY
resultsThe EHR advisory was associated with changes in prescribers' behavior, leading to increased naloxone prescriptions and decreased prescribed opioid doses.
conclusionsEHR advisories are an effective systems-level intervention to enhance the safety of prescribed opioids and increase rates of naloxone prescribing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.