Evidence map›Paper›PMID 36376545›Full record

ArticleJournal of endocrinological investigation2023

A nomogram and risk classification system for predicting cancer-specific survival in tall cell variant of papillary thyroid cancer: a SEER-based study.

X Wang, X Zheng, J Zhu, Z Li, T Wei

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Article in Journal of endocrinological investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

X WangDepartment of Thyroid & Parathyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
X ZhengDepartment of Thyroid & Parathyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
J ZhuDepartment of Thyroid & Parathyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Z LiDepartment of Thyroid & Parathyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
T WeiDepartment of Thyroid & Parathyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, China. docweitao@sina.com.ORCID http://orcid.org/0000-0002-9993-5054

Funding

Sichuan Province Science and Technology Support Program 20ZDYF2669
6 · The paper itself

Abstract

backgroundTall cell variant (TCV) of papillary thyroid cancer (PTC) is the most common aggressive subtype of PTC. The factors that affect survival of patients with TCV remain unclear. We aimed to develop a model to predict the cancer-specific survival (CSS).

methodsA total of 1615 patients diagnosed with TCV between 2004 and 2016 were identified from the Surveillance, Epidemiology, and End Results (SEER) database and randomized into training and validation cohorts (7:3). A predictive nomogram for predicting CSS was constructed by Cox proportional hazards regression and validated by concordance index (C-index), calibration curve, and decision curve analyses (DCA). A risk classification system was built based on the total nomogram scores of each case.

resultsA nomogram was constructed including five independent prognostic factors (age, tumor size, T stage, M stage, and extent of surgery) associated with CSS in TCV patients. Various validations proved that the nomogram model had good consistency and discrimination for TCV prognosis. The risk classification system could perfectly classify TCV patients into three risk groups with significantly different CSS. Compared with traditional AJCC TNM staging system, the nomogram could better predict CSS in TCV patients.

conclusionsA nomogram and corresponding risk classification system were developed for predicting CSS in TCV patients. The model has excellent performance and can be used to help clinicians make accurate prognostic assessment and individualized treatment.

Indexed as

NomogramsThyroid NeoplasmsDatabases, FactualHumansPrognosisThyroid Cancer, PapillaryNomogramPapillary thyroid cancer (PTC)PrognosisSurveillance, epidemiology, and end results program database (SEER)Tall cell variant (TCV)

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.