ArticleThe British journal of ophthalmology2023
Detection of diabetic neovascularisation using single-capture 65°-widefield optical coherence tomography angiography.
Article in The British journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Ultra-widefield optical coherence tomography angiography plus colour fundus photography in von Hippel‒Lindau disease: detection, classification, and correlations with findings on fluorescein angiography.Eye and vision (London, England) · 2026Article
- Retinal Characteristics in Eyes With Retinal Vein Occlusion Using Widefield Swept-Source Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2026Article
- Applicability study of AI attribution methods for ophthalmic image classification.Scientific reports · 2026Article
- Widefield OCT angiography.Progress in retinal and eye research · 2025Review
- Artificial intelligence in managing retinal disease-current concepts and relevant aspects for health care providers.Wiener medizinische Wochenschrift (1946) · 2025Review
- Modern Approach to Diabetic Retinopathy Diagnostics.Diagnostics (Basel, Switzerland) · 2024Review
- The effect of long-term hemodialysis on diabetic retinopathy observed by swept-source optical coherence tomography angiography.BMC ophthalmology · 2024Article
- Controllable editing via diffusion inversion on ultra-widefield fluorescein angiography for the comprehensive analysis of diabetic retinopathy.Biomedical optics express · 2024Article
- A Complete Review of Automatic Detection, Segmentation, and Quantification of Neovascularization in Optical Coherence Tomography Angiography Images.Diagnostics (Basel, Switzerland) · 2023Review
- Comparison of widefield swept-source optical coherence tomographic angiography and fluorescein fundus angiography for detection of retinal neovascularization with diabetic retinopathy.BMC ophthalmology · 2023Observational
- Multiple instance learning based classification of diabetic retinopathy in weakly-labeled widefield OCTA en face images.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the detection rate of retinal neovascularisation (NV) in eyes with proliferative diabetic retinopathy (PDR) using widefield optical coherence tomography angiography (WF-OCTA) in comparison to ultrawidefield fluorescein angiography (UWF-FA).
methodsSingle-capture 65°-WF-OCTA-imaging was performed in patients with NV at the disc or elsewhere (NVE) detected on UWF-FA using a modified PlexElite system and B-scans were examined for blood flow signals breaching the internal limiting membrane. Sensitivity of WF-OCTA and UWF colour fundus (UWF-CF) photography for correct diagnosis of PDR was determined and interdevice agreement (Fleiss' κ) between WF-OCTA and UWF-FA for detection of NV in the total gradable area and each retinal quadrant was evaluated.
resultsFifty-nine eyes of 41 patients with PDR detected on UWF-FA were included. Sensitivity of detecting PDR on WF-OCTA scans was 0.95 in contrast to 0.78 on UWF-CF images. Agreement in detecting NVE between WF-OCTA and UWF-FA was high in the superotemporal (κ=0.98) and inferotemporal (κ=0.94) and weak in the superonasal (κ=0.24) and inferonasal quadrants (κ=0.42). On UWF-FA, 63% of NVEs (n=153) were located in the temporal quadrants with 93% (n=142) of them being detected on WF-OCTA scans.
conclusionThe high reliability of non-invasive WF-OCTA imaging in detecting PDR can improve clinical examination with the potential to replace FA as a single diagnostic tool.
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