Evidence map›Paper›PMID 36375971›Full record

ArticleBMJ open2022

Outpatient parenteral antimicrobial therapy in Germany: a prospective cohort study protocol.

Nadine Scholten, Charlotte Leisse, Vanessa Brandes, Charlotte Oberröhrmann, Peter Ihle, Sophie Peter, Anna Hagemeier, Martin Hellmich, Christoph H Lindemann, Christina Samel and 2 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04002453 (Outpatient Parenteral Antibiotic Therapy in the Metropolitan Area of Cologne), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04002453 unknown statusnot on this map

Outpatient Parenteral Antibiotic Therapy in the Metropolitan Area of Cologne

Typeobservational_patient_registrySponsorUniversity of CologneRan2020 to 2023Enrolled120ConditionsImplementation of OPAT in GermanyArmsOutpatient Parenteral Antibiotic Therapy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Observational
  3. [Outpatient parenteral anti-infective therapy (OPAT)].Innere Medizin (Heidelberg, Germany) · 2024
    Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nadine ScholtenUniversity of Cologne, Faculty of Human Sciences & Faculty of Medicine and University Hospital Cologne, Institute of Medical Sociology, Health Services Research, and Rehabilitation Science, Cologne, Germany.ORCID 0000-0002-7793-7745
Charlotte LeisseDepartment I of Internal Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany charlotte.leisse@uk-koeln.de.ORCID 0000-0002-5562-5038
Vanessa BrandesDepartment I of Internal Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
Charlotte OberröhrmannUniversity of Cologne, Faculty of Human Sciences & Faculty of Medicine and University Hospital Cologne, Institute of Medical Sociology, Health Services Research, and Rehabilitation Science, Cologne, Germany.
Peter IhlePMV research group at the Department of Psychiatry and Psychotherapy for Children and Young Adults, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Sophie PeterUniversity of Cologne, Faculty of Human Sciences & Faculty of Medicine and University Hospital Cologne, Institute of Medical Sociology, Health Services Research, and Rehabilitation Science, Cologne, Germany.
Anna HagemeierInstitute of Medical Statistics and Computational Biology (IMSB), Medical Faculty, University of Cologne, Cologne, Germany.
Martin HellmichInstitute of Medical Statistics and Computational Biology (IMSB), Medical Faculty, University of Cologne, Cologne, Germany.
Christoph H LindemannDepartment II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Christina SamelInstitute of Medical Statistics and Computational Biology (IMSB), Medical Faculty, University of Cologne, Cologne, Germany.
Holger PfaffUniversity of Cologne, Faculty of Human Sciences & Faculty of Medicine and University Hospital Cologne, Institute of Medical Sociology, Health Services Research, and Rehabilitation Science, Cologne, Germany.
Clara LehmannDepartment I of Internal Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID 0000-0002-7042-1578

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOutpatient parenteral antimicrobial therapy (OPAT) means intravenous administration of antibiotics outside the hospital. The antibiotics are administered at the patient's home. The advantages are the shortening of the inpatient stay, which means that patients can remain in their familiar environment, the reduction of nosocomial infections as well as the reduction of hospital and therapy costs. Nevertheless, OPAT is rarely performed in Germany, despite its international application. Therefore, systematic data on OPAT are not available in Germany. The project objective is to investigate the medical care using OPAT under medical, epidemiological and economic aspects within the framework of the Cologne Network of Infectious Diseases. METHODS AND ANALYSIS: Observational study with mixed-methods approach, qualitative analysis to identify physician-side factors to assess the attitude of general practitioners in Cologne with regard to possible implementation barriers of an OPAT. Longitudinal analysis of an OPAT patient cohort with respect to clinical and patient-relevant outcomes using descriptive and conclusive statistics. ETHICS AND DISSEMINATION: The study has been approved by the Institutional Review Board of the University of Cologne, Germany (19-1284-1). Written informed consent was obtained from all participants. The results will be submitted for publication in a peer-reviewed journal and presented at one or more scientific conferences. TRIAL REGISTRATION NUMBER: NCT04002453.

Indexed as

Anti-Infective AgentsOutpatientsAmbulatory CareAnti-Bacterial AgentsGermanyHumansObservational Studies as TopicProspective StudiesAnti-Bacterial AgentsAnti-Infective AgentsGENERAL MEDICINE (see Internal Medicine)INFECTIOUS DISEASESOrganisation of health servicesQuality in health care

Identifiers

PMID36375971
PMCPMC9664305

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.