Evidence map›Paper›PMID 36375454›Full record

ArticleThe American journal of tropical medicine and hygiene2022

A Chikungunya Outbreak in a Dengue-endemic Region in Rural Northern Coastal Ecuador.

Sully Márquez, Gwenyth O Lee, Paulina Andrade, Julio Zuniga, Gabriel Trueba, Joseph N S Eisenberg, Josefina Coloma

Open access · greenAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sully MárquezInstituto de Microbiología, Universidad San Francisco de Quito, Quito, Ecuador.
Gwenyth O LeeDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Paulina AndradeColegio de Ciencias Biológicas y Ambientales COCIBA, Universidad San Francisco de Quito, Quito, Ecuador.
Julio ZunigaDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Gabriel TruebaInstituto de Microbiología, Universidad San Francisco de Quito, Quito, Ecuador.
Joseph N S EisenbergDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Josefina ColomaDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California.
Universidad San Francisco de Quito · ECUniversity of Michigan–Ann Arbor · USUniversity of California, Berkeley · US

Funding

American Asian Centers for Arbovirus Research and Enhanced Surveillance (A2CARES)U01AI151788 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Josefina Coloma, Eva Harris · 2020 to 2026
$9.6M
Zika and Dengue Co-circulation Under Environmental Change and UrbanizationR01AI132372 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLOMA, JOSEFINA, EISENBERG, JOSEPH N. S. · 2017 to 2020
$2.9M
NIAID NIH HHS R01 AI132372NIAID NIH HHS U01 AI151788
6 · The paper itself

Abstract

Dengue virus (DENV) reemerged in the Americas in the 1980s and 1990s, whereas chikungunya virus (CHIKV) emerged in 2014. Although CHIKV produced large epidemics from 2014 to 2017, dengue fever has been the prominent arboviral disease identified through passive surveillance, bringing to question the degree to which cases are misdiagnosed. To address this concern, we conducted an active household-based surveillance of arboviral-like illnesses in six rural and remote communities in northern coastal Ecuador from May 2019 to February 2020. Although passive surveillance conducted by the Ecuadorian Ministry of Health reported only DENV cases in the region, more than 70% of the arbovirus-like illnesses detected by active surveillance in our study were positive for CHIKV. These findings underline the need for active surveillance of arboviral infections with laboratory confirmation, especially in rural communities where arboviral illnesses are more likely to be underreported.

Indexed as

Chikungunya FeverChikungunya virusDengueDengue VirusDisease OutbreaksEcuadorHumansRural Population

Identifiers

PMID36375454
PMCPMC9768284
OpenAlexW4308998776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.