Evidence map›Paper›PMID 36375452›Full record

ArticleThe American journal of tropical medicine and hygiene2022

Leptospira Infection in Rural Areas of Urabá Region, Colombia: A Prospective Study.

Juan C Quintero-Vélez, Juan D Rodas, Carlos A Rojas, Albert I Ko, Elsio A Wunder

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Molecular Characterization ofTropical medicine and infectious disease · 2024
    Article
  7. How market integration impacts human disease ecology.Evolution, medicine, and public health · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juan C Quintero-VélezGrupo de Investigación Ciencias Veterinarias Centauro, Universidad de Antioquia, Medellín, Colombia.
Juan D RodasGrupo de Investigación Ciencias Veterinarias Centauro, Universidad de Antioquia, Medellín, Colombia.
Carlos A RojasGrupo de Epidemiología, Universidad de Antioquia, Medellín, Colombia.
Albert I KoDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut.
Elsio A WunderDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Naturally-Acquired and Vaccine-Mediated Immunity to LeptospirosisR01AI121207 · NIAID · YALE UNIVERSITY · PI KO, ALBERT ICKSANG, REIS, MITERMAYER GALVAO DOS · 2016 to 2020
$6.4M
Research Training Program on the Impact of Zoonotic and Vector-borne Viruses, Rickettsiae, and Leptospira in Acute Undifferentiated Febrile IllnessesD43TW010331 · FIC · UNIVERSITY OF TEXAS MED BR GALVESTON · PI AGUILAR, PATRICIA VERONICA, RODAS, JUAN DAVID · 2016 to 2025
$2.6M
FIC NIH HHS D43 TW010331NCATS NIH HHS UL1 TR001863NIAID NIH HHS R01 AI121207
6 · The paper itself

Abstract

The objective of this study was to analyze the eco-epidemiological aspects of Leptospira seroprevalence and seroincidence and its associated factors in two municipalities of northwest Colombia. A prospective study was performed in rural areas of Urabá, Antioquia, Colombia. The study enrolled 597 people between November 2015 and January 2016, of which 274 were followed up 1 year later. Serologic testing was performed by a microscopic agglutination. The outcomes were seroprevalent and seroincident cases, and the primary exposure was an outdoor occupation. A binary and mixed-effect multinomial logistic regression model was used to estimate factors associated with seroprevalent or seroincident cases of Leptospira infection. The overall Leptospira seroprevalence was 27.81% (95% confidence interval: 23.62-32.49), and the overall cumulative seroincidence for Leptospira was 14.60% (95% confidence interval: 10.33-20.23). Multivariable analysis showed that factors associated with L. interrogans serogroups seropositivity were outdoor occupation, male gender, older age, the presence of dirt floor in the household, and the presence of piglets and opossums. It also showed that factors associated with other Leptospira species serogroups were the presence of pit latrines and of turkeys. In addition, the multivariable model of seroincident cases of L. interrogans serogroups evidenced outdoor occupations, the presence of rats, and corn cultivation as risk factors. Likewise, the multivariable model for seroincident cases of other Leptospira species showed that the presence of hunting canines and cassava cultivation were risk factors. We found specific factors associated with the transmission of Leptospira serogroups contribute to the understanding of the epidemiology of Leptospira infection in rural areas of Urabá, Colombia.

Indexed as

LeptospiraLeptospirosisAnimalsAntibodies, BacterialColombiaDogsMaleProspective StudiesRatsSeroepidemiologic StudiesSwineAntibodies, Bacterial

Identifiers

PMID36375452
PMCPMC9768283

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.