ArticleDevelopmental cognitive neuroscience2022
Longitudinal and prospective assessment of prenatal maternal sleep quality and associations with newborn hippocampal and amygdala volume.
Article in Developmental cognitive neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Sleep During Pregnancy and Offspring Outcomes From Infancy to Childhood: A Systematic Review.Biopsychosocial science and medicine · 2025Pooled it
- Inflammatory exposures in early pregnancy and multidimensional sleep in late pregnancy: a prospective population-based study.Brain, behavior, & immunity - health · 2026Article
- Maternal sleep deprivation and developmental programming of brain aging trajectories in offspring.Biogerontology · 2026Review
- Behavioral Sleep Therapies During the Perinatal Period: A Scoping Review.Current sleep medicine reports · 2026Review
- Daily step-count and sleep metrics across pregnancy: an observational analysis of the LEAP cluster randomized clinical trial.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Neonatal striatal volume is associated with infant anhedonia.Journal of affective disorders · 2026Article
- The association between maternal sleep and circadian rhythms during pregnancy and infant sleep and socioemotional outcomes.European child & adolescent psychiatry · 2025Article
- Social disadvantage is associated with impaired increase in salivary diurnal melatonin amplitude throughout pregnancy.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Association between prenatal maternal sleep quality, neonatal uncinate fasciculus white matter, and infant negative emotionality.EBioMedicine · 2024Article
- The effects of psychotherapy for anhedonia on subcortical brain volumes measured with ultra-high field MRI.Journal of affective disorders · 2024Article
- Impact of prenatal maternal depression on gestational length: post hoc analysis of a randomized clinical trial.EClinicalMedicine · 2024Article
- Maternal anxiety during pregnancy predicts infant attention to affective faces.Journal of affective disorders · 2024Article
- A framework for testing pathways from prenatal stress-responsive hormones to cardiovascular disease risk.Frontiers in endocrinology · 2023Review
- Transdisciplinary fetal-neonatal neurology training integrates women's and children's health with life-course brain capital strategies: a narrative review.Frontiers in neurologyReview
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe rapid maturation of the fetal brain renders the fetus susceptible to prenatal environmental signals. Prenatal maternal sleep quality is known to have important health implications for newborns including risk for preterm birth, however, the effect on the fetal brain is poorly understood.
methodParticipants included 94 pregnant participants and their newborns (53% female). Pregnant participants (M
resultsThe overall trajectory of prenatal maternal sleep quality was associated with hippocampal volume (left: b = 0.00003, p = 0.013; right: b = 0.00003, p = .008). Follow up analyses assessing timing of exposure indicate that poor sleep quality early in pregnancy was associated with larger hippocampal volume bilaterally (e.g., late gestation left: b = 0.002, p = 0.24; right: b = 0.004, p = .11). Prenatal sleep quality was not associated with amygdala volume.
conclusionThese findings highlight the implications of poor prenatal maternal sleep quality and its role in contributing to newborn hippocampal development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.