Evidence map›Paper›PMID 36375214›Full record

ArticleGait & posture2023

Clinical measures of balance and gait cannot differentiate somatosensory impairments in people with lower-limb amputation.

B A Petersen, P J Sparto, L E Fisher

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gait & posture, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

B A PetersenRehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA; Center for the Neural Basis of Cognition, Pittsburgh, PA, USA.
P J SpartoDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA; Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA, USA.
L E FisherRehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA; Center for the Neural Basis of Cognition, Pittsburgh, PA, USA; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. Electronic address: lef44@pitt.edu.
University of Pittsburgh · US

Funding

The effect of spinal cord stimulation on spinal reflex gain and dorsal column sensory pathway and their correlation with phantom limb painUH3NS100541 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FISHER, LEE E, WEBER, DOUGLAS J · 2017 to 2022
$4.6M
Restoring Proprioception to Improve Balance and Gait in Lower-Limb Amputees - COVID-19 SupplementF30HD098794 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PETERSEN, BAILEY ANNE · 2019 to 2022
$120k
NICHD NIH HHS F30 HD098794NINDS NIH HHS UH3 NS100541
6 · The paper itself

Abstract

backgroundIn addition to a range of functional impairments seen in individuals with a lower-limb amputation, this population is at a substantially elevated risk of falls. Studies postulate that the lack of sensory feedback from the prosthetic limb contributes heavily to these impairments, but the extent to which sensation affects functional measures remains unclear. RESEARCH QUESTION: The purpose of this study is to determine how sensory impairments in the lower extremities relate to performance with common clinical functional measures of balance and gait in individuals with a lower-limb amputation. Here we evaluate the effects of somatosensory integrity to clinical and lab measures of static, reactive and dynamic balance, and gait stability.

methodsIn 20 individuals with lower-limb amputation (AMP) and 20 age and gender-matched able-bodied controls (CON), we evaluated the effects of sensory integrity (pressure, proprioception, and vibration) on measures of balance and gait. Static, reactive, and dynamic balance were assessed using the Sensory Organization Test (SOT), Motor Control Test (MCT), and Functional Gait Assessment (FGA), respectively. Gait stability was assessed through measures of step length asymmetry and step width variability. Sensation was categorized into intact or impaired sensation by pressure thresholds and differences across groups were analyzed.

resultsThere were significant differences between AMP and CON groups for reliance on vision for static balance in the SOT, MCT, and FGA (p < 0.01). Despite differences across groups, there were no significant differences within the AMP group based on intact or impaired sensation across all functional measures. SIGNIFICANCE: Despite being able to detect differences between able-bodied individuals and individuals with an amputation, these functional measures cannot distinguish between levels of impairment within participants with an amputation. These findings suggest that more challenging and robust metrics are needed to evaluate the effects of sensation and function in individuals with an amputation.

Indexed as

Artificial LimbsPostural BalanceAmputation, SurgicalGaitHumansHypesthesiaAmputationBalanceGaitSensation

Identifiers

PMID36375214
PMCPMC9970031
OpenAlexW4307569750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.