Evidence map›Paper›PMID 36374939›Full record

ArticlePLoS neglected tropical diseases2022

Independent evaluation of Wolbachia infected male mosquito releases for control of Aedes aegypti in Harris County, Texas, using a Bayesian abundance estimator.

Saul Lozano, Kevin Pritts, Dagne Duguma, Chris Fredregill, Roxanne Connelly

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Wolbachia-carrying Aedes mosquitoes for preventing dengue infection.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Article
  3. Review
  4. The inhibition mechanism ofFrontiers in microbiology · 2026
    Review
  5. Article
  6. ExploitingPathogens (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Microbial gatekeepers: midgut bacteria inFrontiers in microbiology · 2025
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Saul LozanoNational Center for Emerging and Zoonotic Infectious Diseases, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, United States of America.ORCID 0000-0003-1517-6853
Kevin PrittsWestern Gulf Center of Excellence for Vector-Borne Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America.ORCID 0000-0001-8853-6261
Dagne DugumaHarris County Public Health, Mosquito and Vector Control Division, Houston, Texas, United States of America.
Chris FredregillHarris County Public Health, Mosquito and Vector Control Division, Houston, Texas, United States of America.ORCID 0000-0002-2200-6169
Roxanne ConnellyNational Center for Emerging and Zoonotic Infectious Diseases, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, United States of America.ORCID 0000-0003-4141-347X
Centers for Disease Control and Prevention · USHarris Health System · USThe University of Texas Medical Branch at Galveston · US

Funding

ACL HHS U01CK000512NCEZID CDC HHS U01 CK000512
6 · The paper itself

Abstract

Among disease vectors, Aedes aegypti (L.) (Diptera: Culicidae) is one of the most insidious species in the world. The disease burden created by this species has dramatically increased in the past 50 years, and during this time countries have relied on pesticides for control and prevention of viruses borne by Ae. aegypti. The small number of available insecticides with different modes of action had led to increases in insecticide resistance, thus, strategies, like the "Incompatible Insect Technique" using Wolbachia's cytoplasmic incompatibility are desirable. We evaluated the effect of releases of Wolbachia infected Ae. aegypti males on populations of wild Ae. aegypti in the metropolitan area of Houston, TX. Releases were conducted by the company MosquitoMate, Inc. To estimate mosquito population reduction, we used a mosquito abundance Bayesian hierarchical estimator that accounted for inefficient trapping. MosquitoMate previously reported a reduction of 78% for an intervention conducted in Miami, FL. In this experiment we found a reduction of 93% with 95% credibility intervals of 86% and 96% after six weeks of continual releases. A similar result was reported by Verily Life Sciences, 96% [94%, 97%], in releases made in Fresno, CA.

Indexed as

AedesPest Control, BiologicalWolbachiaAnimalsBayes TheoremMaleMosquito VectorsTexas

Identifiers

PMID36374939
PMCPMC9704758
OpenAlexW4308951927

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.