Evidence map›Paper›PMID 36374890›Full record

ArticleIEEE transactions on neural networks and learning systems2024

Contrastive Brain Network Learning via Hierarchical Signed Graph Pooling Model.

Haoteng Tang, Guixiang Ma, Lei Guo, Xiyao Fu, Heng Huang, Liang Zhan

Abstract read
In one paragraph

Article in IEEE transactions on neural networks and learning systems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. A functional system-informed graph neural network framework to quantify interpretable brain dysfunction in ASD.Neural networks : the official journal of the International Neural Network Society · 2026
    Article
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  5. BPEN: Brain Posterior Evidential Network for trustworthy brain imaging analysis.Neural networks : the official journal of the International Neural Network Society · 2025
    Article
  6. Review
  7. Article
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  11. Review
  12. Bidirectional Mapping with Contrastive Learning on Multimodal Neuroimaging Data.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haoteng Tang
Guixiang Ma
Lei Guo
Xiyao Fu
Heng Huang
Liang Zhan

Funding

Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksU01AG068057 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christos Davatzikos, Heng Huang · 2020 to 2026
$20.7M
The Human Connectome Project (HCP)U01MH093765 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2010 to 2014
$12.1M
Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
A Storage Area Network for Structural and Functional Image AnalysisS10RR023401 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2009 to 2009
$2.0M
SILICON GRAPHICS PRISM EXTREME 128P/1TBS10RR023043 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$1.5M
Connecting late-life depression and cognition with statistical physics based connectomics and sparse Frechet regressionRF1MH125928 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LEOW, ALEX, WU, YICHAO · 2021 to 2021
$1.3M
CRCNS: Investigating Brain Dynamics through the Lens of Statistical MechanicsR01AG071243 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEOW, ALEX, ZHAN, LIANG · 2020 to 2022
$882k
Computeserver Structural &Functional Image AnalysisS10RR019307 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2004 to 2004
$496k
NCRR NIH HHS S10 RR019307NCRR NIH HHS S10 RR023043NCRR NIH HHS S10 RR023401NIA NIH HHS R01 AG071243NIA NIH HHS U01 AG068057NIBIB NIH HHS P41 EB015896NIMH NIH HHS RF1 MH125928NIMH NIH HHS U01 MH093765
6 · The paper itself

Abstract

Recently, brain networks have been widely adopted to study brain dynamics, brain development, and brain diseases. Graph representation learning techniques on brain functional networks can facilitate the discovery of novel biomarkers for clinical phenotypes and neurodegenerative diseases. However, current graph learning techniques have several issues on brain network mining. First, most current graph learning models are designed for unsigned graph, which hinders the analysis of many signed network data (e.g., brain functional networks). Meanwhile, the insufficiency of brain network data limits the model performance on clinical phenotypes' predictions. Moreover, few of the current graph learning models are interpretable, which may not be capable of providing biological insights for model outcomes. Here, we propose an interpretable hierarchical signed graph representation learning (HSGPL) model to extract graph-level representations from brain functional networks, which can be used for different prediction tasks. To further improve the model performance, we also propose a new strategy to augment functional brain network data for contrastive learning. We evaluate this framework on different classification and regression tasks using data from human connectome project (HCP) and open access series of imaging studies (OASIS). Our results from extensive experiments demonstrate the superiority of the proposed model compared with several state-of-the-art techniques. In addition, we use graph saliency maps, derived from these prediction tasks, to demonstrate detection and interpretation of phenotypic biomarkers.

Indexed as

BrainConnectomeMachine LearningNeural Networks, ComputerAlgorithmsHumansMagnetic Resonance ImagingModels, NeurologicalNerve Net

Identifiers

PMID36374890
PMCPMC10183052

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.